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Bulletin of Experimental Biology and Medicine

, Volume 123, Issue 1, pp 52–54 | Cite as

Development of increased convulsibility in mice after a single norbornan injection

  • A. I. Golovko
  • M. B. Ivanov
  • T. V. Klyuntina
  • G. A. Sofronov
  • O. A. Sviderskii
  • V. V. Shilov
Pharmacology And Toxicology
  • 30 Downloads

Abstract

A single intraperitoneal injection of norbornan markedly increases convulsant activities of picrotoxin and 3-mercaptopropionic acid in mice. Norbornan may be useful in the investigation of the mechanisms of convulsions.

Key Words

norbornan GABAlytics receptors convulsions 

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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • A. I. Golovko
    • 1
  • M. B. Ivanov
    • 1
  • T. V. Klyuntina
    • 1
  • G. A. Sofronov
    • 1
  • O. A. Sviderskii
    • 1
  • V. V. Shilov
    • 1
  1. 1.Department of Military Toxicology and Medical ProtectionAcademy of Military MedicineSt. Petersburg

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