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The Indian Journal of Pediatrics

, Volume 59, Issue 1, pp 103–108 | Cite as

EEG recognition of holoprosencephaly and aicardi syndrome

  • K. N. Shah
  • Surekha Rajadhyaksha
  • V. S. Shah
  • M. Wakde
Original Articles

Abstract

Two cases of alobar holoprosencephaly and two of Aicardi syndrome are reported for their highly specific electroencephalographic (EEG) changes. The asynchronous sharp waves and spikes over the frontal regions with decreasing gradient of potential to the occipital leads were seen in alobar holoprosencephaly while burst suppression pattern with total asynchrony between the two hemispheres was seen in Aicardi syndrome. Even though EEG changes cannot be pathogenomic of any abnormality, it is suggested that as in conditions like subacute sclerosing panencephalitis and petitmal epilepsy, so also in alobar holoprosencephaly and Aicardi syndrome, the characteristic features seen on EEG may provide the initial clue to the correct diagnosis.

Key words

EEG Holoprosencephaly Aicardi syndrome 

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Copyright information

© Dr. K C Chaudhuri Foundation 1992

Authors and Affiliations

  • K. N. Shah
    • 1
  • Surekha Rajadhyaksha
    • 1
  • V. S. Shah
    • 1
  • M. Wakde
    • 1
  1. 1.Department of Pediatrics, MedicineBai Jerbai Wadia Hospital for Children & Institute of Child HealthBombay

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