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Molecular Biology

, Volume 34, Issue 4, pp 496–507 | Cite as

Molecular mechanisms of early neurogenesis in vertebrates

  • E. M. Alexandrova
  • A. G. Zaraisky
Article

Abstract

Recent studies revealed a great variety of genes which control the early development of the central nervous system in vertebrates, including neural induction and differentiation of primary neurons. Most of these genes were first identified inDrosophila melanogaster, then their structural and functional homologs were found in vertebrates. Modern data on the molecular-genetic mechanisms of vertebrate neurogenesis are reviewed. The neurogenetic mechanisms are compared for vertebrates and invertebrates. Widely discussed hypotheses are considered along with the commonly accepted mechanisms.

Key words

neurogenesis neural induction proneural genes neurogenic genes vertebrates 

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Copyright information

© MAIK “Nauka/Interperiodica” 2000

Authors and Affiliations

  • E. M. Alexandrova
    • 1
  • A. G. Zaraisky
    • 1
  1. 1.Shemyakin and Ovchinnikov Institute of Bioorganic ChemistryRussian Academy of SciencesMoscowRussia

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