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Russian Journal of Electrochemistry

, Volume 36, Issue 6, pp 873–876 | Cite as

Synthesis of aminomethyl derivatives of 3-methyl-4,7-dihydro-3H-imidazo[4,5-d][1,2,3]triazin-4-one

  • G. L. Rusinov
  • R. I. Ishmetova
  • I. S. Selezneva
  • T. A. Kalugina
Article
  • 28 Downloads

Abstract

New aminomethyl derivatives of 3-methyl-4,7-dihydro-3H-imidazo[4,5-d][l,2,3]triazin-4-one were synthesized by Mannich reaction. These Mannich bases is also possible to prepare by reaction of 7(5)-hydroxymethyl-3-methyl-4,7(5)dihydro-3H-imidazo[4,5-d][l,2,3]triazin-4-one with amines. The compounds obtained exist in solutions as mixtures of N5 and N7 isomers, and the fraction of the latter grows with the polarity of the solvent.

Keywords

Ethyl Ether Benzotriazole Mannich Reaction Mannich Base Separate Precipitate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Katritzky, A.R., Jozwiak, A., Lue, P., Yannakopoulou, K., Palenik, G.J., and Ze-Ying Zhang,Tetrahedron, 1990, vol. 46, no. 2, pp. 633–640.CrossRefGoogle Scholar
  2. 2.
    Czech Patent 261442, 1989.Chem. Abstr., 1990, vol. 112, 98541f.Google Scholar
  3. 3.
    Binda, M., Dziklinska, A., Hachiam, A.F.H., and Plenkiewicz, J.,Pol. J. Chem., 1992, vol. 66, no. 8, pp. 1257–1261.Google Scholar
  4. 4.
    Rusinov, G.L., Ishmetova, R.I., and Chupakhin, O.N.,Zh. Org. Khim., 1997, vol. 33, no. 4, pp. 583–590.Google Scholar
  5. 5.
    Selesneva, I.S., Bulychev, Y.N., Zimakova, N.I., Gershanovich, M.L., Pospelova, T.A., and Mokriishm, V.S., Abstracts of Papers,15th Int. Congress of heterocyclic chemistry, Teipei, 1995.Google Scholar
  6. 6.
    Kazitsyna, L.A. and Kupletskaya, N.B.,Primenenie UF-, IK-i YaMR-spektroskopii v organicheskoi khimii (UV, IR, and NMR Application in Organic Chemistry), Moscow: Vysshaya Shkola, 1971.Google Scholar
  7. 7.
    Cross, A.,Vvedenie v prakticheskuyu infrakrasnuyu spektroskopiyu (Introduction to Practical IR spectroscopy), Moscow: Inostr. Lit., 1961.Google Scholar
  8. 8.
    Selezneva, I.S.,Cand. Sci. (Chem.) Dissertation, Sverdlovsk, 1980.Google Scholar

Copyright information

© MAIK “Nauka/Interperiodica” 2000

Authors and Affiliations

  • G. L. Rusinov
    • 1
    • 2
  • R. I. Ishmetova
    • 1
    • 2
  • I. S. Selezneva
    • 1
    • 2
  • T. A. Kalugina
    • 1
    • 2
  1. 1.Institute of Organic Synthesis, Ural DivisionRussian Academy of SciencesYekaterinburgRussia
  2. 2.Ural State Technical UniversityYekaterinburgRussia

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