The Indian Journal of Pediatrics

, Volume 52, Issue 3, pp 303–305 | Cite as

Seroconversion in different age groups after measles vaccination

  • S. M. Saha
  • R. K. Aggarwal
  • D. K. Sood
  • S. N. Saxena
Original Articles


Seroconversion following measles immunisation was studied in 439 children aged below 9 to 25 months. The anlaysis of age specific seroconversion rate revealed that only 78 · 9 per cent children in the age group below 9 months was seroconversion rate was not observed with further increase in the age of immunisation. The finding supports the recommendation that 9–12 months is the earliest age for satisfactory active immunisation against measles in India. The use of potent measles vaccine in the immunisation programme was monitored by potency testing of samples recalled from the field.

Key words

Measles immunisation seroconversion optimum age 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Shah U, Banerji KL, Nanavati AN, Mehta NA: A test survey of measles in a rural community in India.Bull WHO 46: 130, 1972PubMedGoogle Scholar
  2. 2.
    Sinclair S: Vital statistics, India: report on causes of death, model registration 1969.Indian Pediatr 11: 69, 1974PubMedGoogle Scholar
  3. 3.
    Saha SM, Saxena SN: Filter paper disc method of blood collection for testing seroconversion after measles immunisation.Indian J Med Res 77: 409, 1983PubMedGoogle Scholar
  4. 4.
    Saha SM, Sharma SB, Balasubrahmanyan M: Antibodies against measles antigen in the laboratory hourse rhesus and bonnet monkeys.Indian J Med Res 69: 213, 1979PubMedGoogle Scholar
  5. 5.
    Job JS, John TS, Joseph A: Antibody response to measles immunisation in India.Bull WHO 62: 737, 1984PubMedGoogle Scholar
  6. 6.
    World Health Organisation: a collaborative study. Seroconversion rates and measles antibody titres induced by measles vaccine in Latin American children 6–12 months of age.Bull Pan Am Helth Org 16: 272, 1982Google Scholar
  7. 7.
    Directorate General of Health Services, Nirman Bhavan, New Delhi, Measles immunisation project, 1981.Google Scholar
  8. 8.
    Shasby DM, Shope TC, Downs H, Hermann K, Polkowki J: Epidemic measles in a highly vaccinated population.N Engl J Med 296: 585, 1977PubMedCrossRefGoogle Scholar
  9. 9.
    Krugman RD: Further attenuated measles vaccine. The need for revised recommendation.J Pediatr 91: 766, 1977PubMedCrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 1985

Authors and Affiliations

  • S. M. Saha
    • 1
  • R. K. Aggarwal
    • 1
  • D. K. Sood
    • 1
  • S. N. Saxena
    • 1
  1. 1.Central Research InstituteKasauli

Personalised recommendations