Plasmid mediated enterotoxin production and drug resistance amongstEscherichia coli from cases of infantile diarrhea
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Seventy enterotoxigenic Esch. coli strains (18LT+; 46ST+ and 6LT+ST †) isolated from infants and children with acute diarrhea were studied for the prevalence of R factor and also for enterotoxin (Ent†) plasmid transfer. These strains were received at the National Salmonella and Escherichia Centre, Central Research Institute, Kasauli during 1981. Sixty one strains were found to be resistant to two or more drugs and 9 were sensitive to all the drugs. Of the total, 24 (34·2%) strains showed the presence of conjugative plasmid; of these 10 (41%) strains showed transfer of Ent† plasmid, of the 24 strains 6 strains were positive for LT and 18 for ST. Of the 6 LT† strains which showed presence of R factor, Ent+ plasmid could be demonstrated in four strains and out of 18 ST† strains Ent† plasmid could be transferred in six Esch. coli strains.
Key wordsPlasmid-enterotoxin-drug resistance- Esch coli
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