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The Indian Journal of Pediatrics

, Volume 60, Issue 4, pp 539–549 | Cite as

Bone marrow transplantation

  • T. S. Vats
Symposium: Hematology/Oncology—II
  • 26 Downloads

Summary

Bone marrow transplantations have a definite role in treatment of leukemias and lymphomas. In acute myeloid leukemia and CML an allogeneic transplant using an HLA identical donor certainly provides a far superior survival than chemotherapy. Patients with Ph’ chromosome need to be transplanted in first remission if a suitable donor is available. In recurrent lymphomas the best results are chieved if the patient is transplanted in complete remission. Transplantation done using minor mismatched family donors or unrelated donors are still considered experimental and more data is needed before final recomendations can be made. Availability of supportive services is an absolute must prior to establishing transplant program. Selection of patients for transplantation should be done after carefully reviewing the indications and discussing with the family the emotional, financial and physical burden of the procedure. For selected indications in leukemias and lymphomas, BMT may be the only viable treatment option and therefore must be considered.

Keywords

Acute Lymphoblastic Leukemia Bone Marrow Transplantation Chronic Myeloid Leukemia BCNU Autologous Bone Marrow Transplantation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Dr. K C Chaudhuri Foundation 1993

Authors and Affiliations

  • T. S. Vats
    • 1
  1. 1.Pediatric Hematology/OncologyUniversity of Kansas Medical CenterKansas CityU.S.A.

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