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The Indian Journal of Pediatrics

, Volume 26, Issue 11, pp 399–405 | Cite as

A study of alpha-ketoacids in protein malnutrition

  • K. C. Chaudhuri
  • J. Nag Chaudhuri
  • S. P. Ghosal
Original Articles

Summary

  1. 1.

    Pyruvic acid and alpha-ketoglutaric acid were estimated in blood and urine of seven marasmic and three normal children.

     
  2. 2.

    A new electrophoretic method of separation of DANB derivatives of pyruvic acid and alpha-ketoglutaric acid has been described.

     
  3. 3.

    The pyruvic and alpha-ketoglutaric acid levels in blood were raised when compared to that of normal.

     
  4. 4.

    The urinary excretion of pyruvic and alpha-ketoglutaric acids were found to be less in the morning samples than in the normals.

     
  5. 5.

    The nature of derangement of the Kreb's cycle in marasmus is discussed.

     

Keywords

Succinic Acid Normal Child Pyruvic Acid Malnourished Child Protein Malnutrition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    El Hawary, M. F. S. andThompson, R. H.S.—Separation and estimation of blood ketoacids by paper chromatography.Biochem J.,53: 340, 1953.Google Scholar
  2. 2.
    Hockenhull, D. J. D. andFloodgate, G. D. O.—Phenylenediamine and 1∶2 diamino-4-nitrobenzene as reagents for alpha-ketoacids.Biochem. J.,52: 38, 1952.PubMedGoogle Scholar
  3. 3.
    Mukherji, K. L. andSarkar, N. K.—Liver enzymes in human under-nutrition.Brit. J. Nutr.,121: 1, 1958.CrossRefGoogle Scholar
  4. 4.
    Neish, J. P.—Methods of biochemical analyses.Interscience Publishers, Vol. 5, p. 107, 1957.Google Scholar
  5. 5.
    Taylor, K. W. andSmith, M. J.—1∶2 diamino-4-nitrobenzene as a reagent for the detection and determination of alpha-ketoacids in blood and urine.Analyst,80: 607, 1955.CrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 1959

Authors and Affiliations

  • K. C. Chaudhuri
    • 1
  • J. Nag Chaudhuri
    • 1
  • S. P. Ghosal
    • 1
  1. 1.Calcutta

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