Pulmonary sequestration with high levels of tumor markers tending to be misdiagnosed as lung cancer

  • Hidehito Matsuoka
  • Hideaki Nohara
Case Report


A 62-year-old man with hemoptysis and an abnormal shadow on chest roentgenogram was diagnosed as having anomalous systemic arterial supply to the normal basal segment of the left lower lobe. The preoperative serum carbohydrate antigen 19–9 and carcinoembryonic antigen levels were 73.8 units/ml and 10.8 ng/ml, respectively. Histopathological examination confirmed that the lesion was an intralobar pulmonary sequestration without air connection. There was no malignant finding in the resected specimen. The serum values of tumor markers returned to their approximate normal ranges after lower lobectomy.

Key words

pulmonary sequestration tumor marker lung cancer 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Pryce DM Lower accessory pulmonary artery with intralobar sequestration of lung: A report of seven cases. J Pathol 1946; 58: 457–67.CrossRefGoogle Scholar
  2. 2.
    Sade RM, Clouse M, Ellis FH Jr. The spectrum of pulmonary sequestration. Ann Thorac Surg 1974; 18: 644–58.PubMedCrossRefGoogle Scholar
  3. 3.
    Bell-Thomson J, Missier P, Sommers SC Lung carcinoma arising in bronchopulmonary sequestration. Cancer 1979; 44: 334–9.PubMedCrossRefGoogle Scholar
  4. 4.
    Juettner FM, Pinter HH, Friehs GB, Hoefler H. Bronchial carcinoid arising in intralobar bronchopulmonary sequestration with vascular supply from the left gastric artery. Case report. J Thorac Cardiovasc Surg 1985; 90: 25–8.PubMedGoogle Scholar
  5. 5.
    Gatzinsky P, Olling S A case of carcinoma in intralobar pulmonary sequestration. Thorac Cardiovasc Surg 1988; 36: 290–1.PubMedCrossRefGoogle Scholar
  6. 6.
    Yagyu H, Adachi H, Furukawa K, Nakamura H, Sudoh A, Oh-ishi S, et al. Intralobar pulmonary sequestration presenting increased serum CA19–9 and CA125. Intern Med 2002; 41: 875–8.PubMedGoogle Scholar
  7. 7.
    Nakamura H, Katsumi T, Nagata S, Saito M, Konaka C, Kato H. A resected case of intralobar pulmonary sequestration with increased serum tumor markers, CA19–9, CA125 and NCC-ST-439 (Eng abstr). Nihon Kyobu Shikkan Gakkai Zasshi 1997; 35: 1425–9.PubMedGoogle Scholar
  8. 8.
    Sekiya M, Chiba A, Ienaga H, Ueki J, Hasunuma K, Takahashi H, et al. Intralobar pulmonary sequestration presenting increased serum CEA, CA 19–9, and CA 125, and associated with asymptomatic pulmonary aspergillosis (Eng abstr). Nihon Kokyuki Gakkai Zasshi 1999; 37: 433–7.PubMedGoogle Scholar
  9. 9.
    Hessel EA 2nd, Boyden EA, Stamm SJ, Sauvage LR. High systemic origin of the sole artery to the basal segments of the left lung: Finding, surgical treatment, and embryologic interpretation. Surgery 1970; 67: 624–32.PubMedGoogle Scholar
  10. 10.
    Wan IY, Lee TW, Sihoe AD, Ng CS, Yim AP Video-assisted thoracic surgery lobectomy for pulmonary sequestration. Ann Thorac Surg 2002; 73: 639–40.PubMedCrossRefGoogle Scholar

Copyright information

© Japanese Association for Thoracic Surgery 2006

Authors and Affiliations

  • Hidehito Matsuoka
    • 1
  • Hideaki Nohara
    • 1
  1. 1.Department of SurgeryHyogo Prefectural Kaibara HospitalTanba, HyogoJapan

Personalised recommendations