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Endocrine Pathology

, Volume 8, Issue 2, pp 87–90 | Cite as

Criteria for malignancy in pancreatic endocrine tumors

  • Carlo Capella
  • Stefano La Rosa
  • Enrico Solcia
Editorial

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References

  1. 1.
    Frantz VK. Tumors of the pancreas. Atlas of tumor pathology, 1st series, fascicles 27 and 28. Washington D.C.: Armed Forces Institute of Pathology, 1959.Google Scholar
  2. 2.
    Cubilla AL, Hajdu SI. Islet cell carcinoma of the pancreas. Arch Pathol 99:671–678, 1975.Google Scholar
  3. 3.
    Klöppel G, Heitz PU. Pancreatic endocrine tumors. Pathol Res Pract 183:155–168, 1988.PubMedGoogle Scholar
  4. 4.
    Solcia E, Sessa F, Rindi G, Bonato M, Capella C. Pancreatic endocrine tumors: general concepts; nonfunctioning tumors and tumors with uncommon function. In: Dayal Y, ed. Endocrine pathology of the gut and pancreas. Boca Raton: CRC, 1991; 105–131.Google Scholar
  5. 5.
    Broder LE, Carter SK, Pancreatic islet cell carcinoma. Clinical features of 52 patients. Ann Intern Med 79:101–107, 1973.PubMedGoogle Scholar
  6. 6.
    Kenny BD, Sloan JM, Hamilton PW, Watt PCH, Johnston CF, Buchanan KD. The role of morphometry in predicting prognosis in pancreatic islet cell tumors. Cancer 64:460–465, 1989.PubMedCrossRefGoogle Scholar
  7. 7.
    Weber HC, Venson DY, Lin JT, Fishbein VA, Orburch M, Strader DB, Gibril F, Metz DC. Determinants of metastatic rate and survival in patients with Zollinger-Ellison syndrome: a prospective long-term study. Gastroenterology 108:1637–1649, 1995.PubMedCrossRefGoogle Scholar
  8. 8.
    Grama D, Eriksson B, Mårtensson H, Cedermark B, Ahrén B, Kristoffersson A, Rastas J, Öberg K, Åkerström G. Clinical characteristics, treatment and survival in patients with pancreatic tumors causing hormonal syndromes. World J Surg 16:632–639, 1992.PubMedCrossRefGoogle Scholar
  9. 9.
    Frantz VK. Tumors of islet cells with hyper-insulinism: benign, malignant and questionable. Ann Surg 112:116–176, 1940.CrossRefGoogle Scholar
  10. 10.
    La Rosa S, Sessa F, Capella C, Riva C, Leone BE, Klersy C, Rindi G, Solcia E. Prognostic criteria in nonfunctioning pancreatic endocrine tumours. Virchows Arch 429: 323–333, 1996.PubMedCrossRefGoogle Scholar
  11. 11.
    Alanen KA, Joensuu H, Klemi PJ, Marin S, Alavaikko M, Nevalainen TJ. DNA ploidy in pancreatic neuroendocrine tumors. Am J Clin Pathol 93:784–788, 1990.PubMedGoogle Scholar
  12. 12.
    Höfler H, Ruhri C, Pütz B, Wirnsberger G, Hauser H. Oncogene expression in endocrine pancreatic tumors. Virchows Arch [B] 55:355–361, 1988.Google Scholar
  13. 13.
    Heitz PU, Kasper M, Klöppel G, Polak JM, Vaitukaitis JL. Glycoprotein-hormone alphachain production by pancreatic endocrine tumors: a specific marker for malignancy. Cancer 51:277–282, 1983.PubMedCrossRefGoogle Scholar
  14. 14.
    Rüschoff J, Willemer S, Brunzel M, Trautmann ME, Frank M, Arnold R, Klöppel G. Nucleolar organizer regions and glycoproteinhormone alpha-chain reaction as markers of malignancy in endocrine tumors of the pancreas. Histopathology 22:51–57, 1993.PubMedCrossRefGoogle Scholar
  15. 15.
    Pelosi G, Zamboni G, Doglioni C, Rodella S, Bresaola E, Iacono C, Serio G, Iannucci A, Scarpa A. Immunodetection of proliferating cell nuclear antigen assesses the growth fraction and predicts malignancy in endocrine tumors of the pancreas. Am J Surg Pathol 16:1215–1225, 1992.PubMedCrossRefGoogle Scholar
  16. 16.
    Pelosi G, Zamboni G. Proliferation markers and their uses in the study of endocrine tumors. Endocr Pathol 7:103–119, 1996.PubMedGoogle Scholar
  17. 17.
    Viale G, Doglioni C, Gambacorta M, Zamboni G, Coggi G, Bordi C. Progesterone receptors immunoreactivity in pancreatic endocrine tumors. Cancer 70:2268–2277, 1992.PubMedCrossRefGoogle Scholar
  18. 18.
    Bordi C, Pilato FP, D’Adda T. Comparative study of seven neuroendocrine markers in pancreatic endocrine tumors. Virchows Arch [A] 413:387–398, 1988.Google Scholar
  19. 19.
    Donow C, Baisch H, Heitz PU, Klöppel G. Nuclear DNA content in 27 pancreatic endocrine tumours: correlation with malignancy, survival and expression of glycoprotein hormone alpha chain. Virchows Arch [A] 419:463–468, 1991.CrossRefGoogle Scholar
  20. 20.
    Nauck M, Creutzfeldt W. Insulin producing tumors and the insulinoma syndrome. In: Dayal Y, ed. Endocrine pathology of the gut and pancreas. Boca Raton: CRC, 1991; 195–226.Google Scholar
  21. 21.
    Ruttman E, Klöppel G, Bommer G, Kiehn M, Heitz PU. Pancreatic glucagonoma with and without syndrome. Immunocytochemical study of 5 tumor cases and review of the literature. Virchows Arch [A] 388:51–67, 1980.CrossRefGoogle Scholar
  22. 22.
    Capella C, Heitz PU, Höfler H, Solcia E, Klöppel G. Revised classification of neuroendocrine tumors of the lung, pancreas and gut. Virchows Arch 425:547–560, 1995.PubMedCrossRefGoogle Scholar

Copyright information

© Humana Press Inc 1997

Authors and Affiliations

  • Carlo Capella
    • 1
  • Stefano La Rosa
    • 1
  • Enrico Solcia
    • 2
  1. 1.Department of Clinical and Biological SciencesUniversity of Pavia at VareseVareseItaly
  2. 2.Department of Human and Hereditary PathologyUniversity of PaviaPaviaItaly

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