Advertisement

The Indian Journal of Pediatrics

, Volume 72, Issue 5, pp 441–442 | Cite as

Bruck syndrome

  • Vikram Datta
  • Aditi Sinha
  • Arvind Saili
  • Sushma Nangia
Clinical Brief

Abstract

The combination of arthrogryposis multiplex congenita and osteogenesis imperfecta is extremely rare. This combination is named Bruck syndrome. A 34 week male baby weighing 1.7 kg at birth was noted to have multiple flexion contractures and pterygia at elbows, wrists and knees, in addition to right foot talipes equinovarus deformity. Postnatally the child developed multiple swellings involving both the upper and lower limbs. A plain radiograph revealed the presence of fractures involving the long bones of the upper and lower limbs. A diagnosis of osteogenesis imperfecta with arthrogryposis multiplex congenita was made, and the patient was labeled as a case of Bruck Syndrome. The aim of this report is to make the readers aware regarding this rare entity and to specifically look for presence of features suggestive of osteogenesis imperfecta when encountered with a neonate born with arthrogryposis multiplex congenita.

Key words

Arthrogryposis Osteogenesis imperfecta Bruck syndrome Neonate 

References

  1. 1.
    Sillence DO. Disorders of bone density,volume and mineralisation. In Emery and Rimoins, eds.Principles and Practice of Medical Genetics. Vol.3 4th edn. Philadelphia; Churchill Livingstone, 2002; 4116–4126.Google Scholar
  2. 2.
    Bruck A.Ueber eine seltene Form von Erkrankung der Knochen und Gelenke.Dtsch Med Wochenschr 1897; 23:152–155.CrossRefGoogle Scholar
  3. 3.
    Sharma NL, Anand JS. Osteogenesis imperfecta with arthrogryposis multiplex congenita.Indian Med J 1964; 53:124–126.Google Scholar
  4. 4.
    Brenner RE, Vetter U, Stoss H, Muller PK, Teller WM. Defective collagen fibril formation and mineralization in osteogenesis imperfecta with congenital joint contractures.Eur J Pediatr 1993; 152:505–508.PubMedCrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2005

Authors and Affiliations

  • Vikram Datta
    • 1
  • Aditi Sinha
    • 1
  • Arvind Saili
    • 1
  • Sushma Nangia
    • 1
  1. 1.Department of PediatricsKalawati Saran Children’s Hospital, Lady Hardinge Medical CollegeNew DelhiIndia

Personalised recommendations