The Indian Journal of Pediatrics

, Volume 66, Issue 5, pp 751–757 | Cite as

Antenatal urologic intervention: current status

  • Jayant Radhakrishnan
  • Kannan Manickam
  • Mark Holterman
  • Ai-Xuan Holterman
Symposium: Neonatal Surgery


The devastation caused by fetal obstructive uropathy is now well known. At the most severe end of the spectrum of obstructive uropathy not only is the developing kidney damaged but the resultant oligohydra-mnios prevents pulmonary development and causes skeletal defects. The most significant changes are noted in patients with posterior urethral valves (PUV). The obvious solution to the problem is to either correct or by pass the obstruction prior to the development of permanent changes. Unfortunately, this simple concept is not easy to apply since it raises numerous ethical, legal, economic and technical problems.

Key words

Oligohydramnios Skeletal defects 


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Copyright information

© Dr. K C Chaudhuri Foundation 1999

Authors and Affiliations

  • Jayant Radhakrishnan
    • 1
  • Kannan Manickam
    • 1
  • Mark Holterman
    • 1
  • Ai-Xuan Holterman
    • 1
  1. 1.Division of Pediatric SurgeryThe University of IllinoisChicagoUSA

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