The Indian Journal of Pediatrics

, Volume 66, Issue 5, pp 663–668 | Cite as

Effect of lactobacillus supplementation on immune status of malnourished pre-school children

  • Sucharitha Devi
  • P. Yasoda Devi
  • M. Siva Prakash
Original Article


The present study was undertaken to assess the effect of Lactobacillus supplementation on immune response of pre school children. Thirty malnourished (grade I and grade II) preschool (3–5 years old) children were selected for the study. These were further categorized into three groups ‘A’, ‘B’ and ‘C’, each group comprising of 10 individuals. Groups ‘Ar and ‘B’ were given lactobacillus supplementation 1.0 x 108 million viable spores/day/child and 2.0 x 108 million of viable spores/day/child for 90 days respectively. Group ’C served as control. Serum adenosine deaminase (ADA) which is an important immunoenzyme marker for assessing lymphocyte function and proliferation was determined at different intervals. The results revealed that lactobacillus supplementation at level of 1.0 x 108 million viable spores/day/child for 15 days along with regular diet significantly improved the ADA levels of pre-school children indicating therapeutic value of lactobacillus as supplementation to malnourished pre-school children.

Key words

Lactobacillus Adenosine deaminase (ADA) Pre-school children 


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Copyright information

© Dr. K C Chaudhuri Foundation 1999

Authors and Affiliations

  • Sucharitha Devi
    • 1
  • P. Yasoda Devi
    • 2
  • M. Siva Prakash
    • 3
  1. 1.Departments of Foods and NutritionPost-graduate and Research Centre, ANGR onAgricultural UniversityHyderabad
  2. 2.Departments of Foods and NutritionCollege of Home Science, BapattaHyderabad, Andhra Pradesh
  3. 3.Departments of Foods and NutritionNational Institute of Nutrition, Jamia-OsmaniaTarnaka, Hyderabad

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