The Indian Journal of Pediatrics

, Volume 69, Issue 5, pp 437–439 | Cite as

Glial choristoma

  • P. Bajaj
  • B. S. Shubha
  • K. Agarwal
  • C. Aggarwal
Clinical Brief


Glial choristoma is a developmental malformation of heterotopic central nervous tissue with limited growth potential. It is considered to be one of the very rare choristomatous lesions involving the oral cavity. This report details the morphological characteristics of glial choristoma arising from the palate in a newborn. Bulk of the tissue comprised of mature neuroglial tissue with astrocytes representing developing brain, cystic spaces lined by cuboidal epithelium indicating ependymal layer. Clinical features, associated malformations and histomorphology of this lesion is discussed.

Key words

Glial choristoma Oral cavity Newborn 


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  1. 1.
    Halperin EC. Neonatal neoplasms.Int J Radiat Oncol Biol Phys 2000; 47(1): 171–178.PubMedCrossRefGoogle Scholar
  2. 2.
    Chou L, Hansen LS, Daniels TE. Choristomas of the oral cavity: A review.Oral Surg Oral Med Oral Pathol 1991; 72 : 584–931.PubMedCrossRefGoogle Scholar
  3. 3.
    Abdelsayed RA, Bent JP, Sharpe DE. Glial choristoma of the tongue: A case report and review of literature.Oral Surg Med Oral Pathol Oral Radiol Endod 1999; 87(2) : 215–222.CrossRefGoogle Scholar
  4. 4.
    Strome SE, McClatchey K, Kileny PR, Koopman CF. Neonatal choristoma of the tongue containing glial tissue: diagnosis and surgical considerations,Int J Pediatr Otorhinolaryngol 1995; 33(3) : 265–273.PubMedCrossRefGoogle Scholar
  5. 5.
    Shinoyama T. Glial choristoma in the oral cavity: histopathological and immunohistochemical features.J Oral Pathol Med 1997; 26(3) : 147–150.CrossRefGoogle Scholar
  6. 6.
    Walker EA Jr, Resler DI. Nasal glioma.Laryngoscope 1963; 73: 93–107.PubMedCrossRefGoogle Scholar
  7. 7.
    Crosby JF. Unusual nasal tumors in children: Glioma and rhabdomyosarcoma.Plast Reconstr Surg 1957; 19 : 143–149.CrossRefGoogle Scholar
  8. 8.
    Borsanyi S. Nasal glioma.Arch Otolanjngol 1960; 72: 376–379.Google Scholar
  9. 9.
    Zarem HA, Gray FG, Morehead D, Edgerton MT. Heterotopic brain in the nasopharynx and soft palate. Report of two cases.Surgery 1967; 61: 483–486.PubMedGoogle Scholar
  10. 10.
    Low NL, Scheinberg L, Anderson DH. Brain tissue in the nose and throat.Pediatrics 1956; 18: 254–259.PubMedGoogle Scholar
  11. 11.
    Emamy H, Almadian H. Limbal dermoid with ectopic brain tissue.Arch Opthalmol 1977; 95: 2201–2202.Google Scholar
  12. 12.
    Newman NJ, Miller NR, Green WR. Ectopic brain in the orbit.Ophthalmology 1986; 93: 268–272.PubMedGoogle Scholar
  13. 13.
    Potter EL, Craig JM. Pathology of the fetus and the infant. 3rd edn. Chicago. Year Book, 1975; 310.Google Scholar
  14. 14.
    Dermott MB, Glasner SD, Nielsen PL, Dehner LP. Soft tissue gliomatosis. Morphologic unity and histogenetic diversity.Am J Surg Pathol 1996; 20: 148–155.CrossRefGoogle Scholar
  15. 15.
    Robinson SHG. Gliomata of the nose and oral cavity: a report of two cases.J Pathol Bact 1946; 58 : 643–648.CrossRefGoogle Scholar
  16. 16.
    Vk Melrin FM, Reed JM, Parent AD. Nasopharyngeal gliomas: Diagnostic and treatment considerations.Otolaryngol Head Neck Surg 1993; 109 : 534–539.Google Scholar
  17. 17.
    Al-Nafussi A, Hancock K, Sommerlad B, Carder PJ. Heterotopic brain tissue presenting as a cystic mass of the palate.Histopathology 1990; 17: 81–84.PubMedCrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2002

Authors and Affiliations

  • P. Bajaj
    • 1
  • B. S. Shubha
    • 1
  • K. Agarwal
    • 1
  • C. Aggarwal
    • 1
  1. 1.Department of PathologyLady Hardinge Medical College & Kalawati Saran Children’s HospitalNew DelhiIndia

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