Fetal intracranial hemorrhage due to antenatal low dose aspirin intake
- 71 Downloads
Antenatal intake of low dose aspirin is advised 1,2 for prevention of pregnancy induced hypertension, intrauterine growth retardation and pre-term labour. Aspirin has an anticoagulant effect due to its action onCyclo-oxygenase and vitamin K dependant coagulation factors. It can readily cross the placental barrier and be a potential cause for bleeding tendency in the fetus. Fetal intracranial hemorrhage, following low dose aspirin administration in a mother and subsequent effect after delivery is being reported.
Key wordsFoetal Intracranial haemorrhage Antenatal aspirin
- 3.Louden KA, Kilbey MD. Low dose aspirin: The rationale for preventing pre-eclampsia and intrauterine growth retardation : A role after CLASP. In Bonnar J, ed.Recent Advances in Obstetrics and Gynecology. New York: Churchill Livingstone, 1995; 15–33.Google Scholar
- 4.Rumack CM, Guggenheim MA, Rumack BHet al. Neonatal Intracranial hemorrhage and maternal use of aspirin.Obstet Gynecol 1981; 58 (Suppl): 525–565.Google Scholar
- 6.Roy AF. Ultrasound Evaluation of the Fetal Neural Axis. In Callen PW, ed.Ultrasonography in Obstetrics and Gynecology. 3rd edn. Philadephia; W.B. Saunders Company, 1994; 189–218.Google Scholar