, Volume 163, Issue 1, pp 257–273 | Cite as

Pulmonary vasculitis

  • David B. Chandler
  • Jack D. Fulmer


The pulmonary vasculitides are a heterogeneous group of diseases characterized by inflammation and sometimes destruction of blood vessels. Most occur as part of a disseminated process, but some are confined to lung. While an etiologic classification is preferable, one approach is to consider these diseases in order of frequency of lung involvement. The pathogenesis of pulmonary vasculitis is not known, but current data suggest that acute vasculitic syndromes are caused by immune-complex deposition and activation of the complement cascade. The chronic and granulomatous vasculitic syndromes may be associated with alterations in cellular-mediated immunity. A brief overview of the major vasculitic syndromes and their management is presented.

Key words

Pulmonary vasculitis Pulmonary granulomatosis 


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Copyright information

© Springer-Verlag New York, Inc 1985

Authors and Affiliations

  • David B. Chandler
    • 1
  • Jack D. Fulmer
    • 1
  1. 1.Department of Medicine, Division of Pulmonary and Critical Care MedicineThe University of Alabama at Birmingham and the Veterans Administration Medical CenterBirmingham

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