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Journal of Chemical Sciences

, Volume 116, Issue 1, pp 49–53 | Cite as

Anodically generated manganese(III) sulphate for the oxidation of dipeptides in aqueous sulphuric acid medium: A kinetic study

  • M. N. Kumara
  • D. Channe Gowda
  • A. Thimme Gowda
  • K. S. Rangappa
Article

Abstract

The kinetic of oxidation of dipeptides (DP) namely valyl-glycine (Val-Gly), alanyl-glycine (Ala-Gly) and glycyl-glycine (Gly-Gly), by Mn(III) have been studied in the presence of sulphate ions in acid medium at 26°C. The reaction was followed spectrophotometrically at λmax = 500 nm. A first-order dependence of the rate on both [Mn(III)]o and [DP]o was observed. The rate is independent of the concentration of reduction product, Mn(II) and hydrogen ions. The effects of varying the dielectric constant of the medium and addition of anions such as sulphate, chloride and perchlorate were studied. The activation parameters have been evaluated using Arrhenius and Eyring plots. The oxidation products were isolated and characterized. A mechanism involving the reaction of DP with Mn(III) in the rate-limiting step is suggested. An apparent correlation was noted between the rate of oxidation and the hydrophobicity of these dimers, where increased hyphobicity results in increased rate of oxidation

Keywords

Oxidation dipeptides manganese(III) 

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Copyright information

© Indian Academy of Sciences 2004

Authors and Affiliations

  • M. N. Kumara
    • 1
  • D. Channe Gowda
    • 1
  • A. Thimme Gowda
    • 2
  • K. S. Rangappa
    • 1
  1. 1.Department of Studies in ChemistryUniversity of MysoreManasagangothri, MysoreIndia
  2. 2.Department of ChemistryAVK College for WomenHassanIndia

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