, Volume 28, Issue 3–4, pp 657–676 | Cite as


  • P. Ramachandra Rao


The well-organised multifunctional structures, systems and biogenic materials found in nature have attracted the interest of scientists working in many disciplines. The efforts have resulted in the development of a new and rapidly growing field of scientific effort called biomimetics. In this article we present a few natural materials and systems and explore how ideas from nature are being interpreted and modified to suit efforts aimed at designing better machines and synthesising newer materials.


Biomimetics biomineralisation supramolecular chemistry hierarchical structures 


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  1. Addadi L, Weiner S 1997 A pavement of pearl.Nature (London) 389: 912–915CrossRefGoogle Scholar
  2. Almqvist N, Thomson N H, Smith B L, Stocky G D, Morse D E, Hansma P K 1999 Methods of fabricating and characterising anew generation of biomimetic materialsMater.Sci. Eng. C7: 37–43Google Scholar
  3. Amada S 1995 Hierarchical functionally gradient structures of bamboo, barley and corn.Mater. Res. Soc. Bull. 20: 35–36Google Scholar
  4. Anderson J C, Eriksson C 1970 Piezoelectric properties of dry and wet bone.Nature (London) 227: 491–492CrossRefGoogle Scholar
  5. Archibald D D, Mann S 1993 Template mineralisation of self-assembled anisotropic lipid microstructures.Nature (London) 364: 430–433CrossRefGoogle Scholar
  6. ATIP 1999 Biomimetic systems R & D in Japan. Asian Technology Information Program (ATIP), TokyoGoogle Scholar
  7. Ball P 1996 Living factories.New Scientist 3rd February: 28–31Google Scholar
  8. Beniash E, Aizenberg J, Addadi L 1997 Amorphous calcium carbonate transforms into calcite during sea urchin larval spicule growth.Proc. R Soc. London B264: 461–465CrossRefGoogle Scholar
  9. Benyus J M 1997Biomimicry: Innovation inspired by nature (New York: William Morrow)Google Scholar
  10. Berman A, Addadi L, Weiner S 1988 Interactions of sea-urchin skeleton macromolecules with growing calcite crystals — a study of intracrystalline proteins.Nature (London) 331: 546–548CrossRefGoogle Scholar
  11. Berman A, Hanson J, Leiserowitz L, KoetzleTF, Weiner S, Addadi L 1993 Biological control of crystal texture: A widespread strategy for adapting crystal properties to function.Science 259: 776–779CrossRefGoogle Scholar
  12. Biaconi P A, Lin J, Strezelecki A R 1991 Crystallisation of an inorganic phase controlled by a polymer matrix.Nature (London) 349: 315–317CrossRefGoogle Scholar
  13. Birchall J D, Thomas N L 1983 On the architecture and function of cuttlefish bone.J. Mater. Sci. 18: 2081–2086CrossRefGoogle Scholar
  14. Brown S, Sarikaya M, Johnson E 2000 A genetic analysis of crystal growth.J. Mol. Biol. 299: 725–735CrossRefGoogle Scholar
  15. Calvert P 1992 Biomimetic ceramics and composites.MRS Bull. 17: 37–40Google Scholar
  16. Calvert P 1996 Biomimetic processing. InProcessing of ceramics: Part II (ed.) R J Brook (Weinheim: VCH)Google Scholar
  17. Cha J N, Stocky G D, Morse D E, Deming T J 2000 Biomimetic synthesis of ordered silica structures mediated by block copolypeptides.Nature (London) 403: 289–292CrossRefGoogle Scholar
  18. Chan V-H, Hoffman J, Lee V Y, Latroce H, Avgeropolous A, Hadfichristidis N, Milter R D, Thomas E L 1999 Ordered bi continuous nanoporous and nanorelief ceramic films from self assembling polymer precurssors.Science 286: 1716–1719CrossRefGoogle Scholar
  19. Chatteigner D, Hedegaard C, Wenk H R 2000 Mollusc shell microstructures and crystallographic textures.J. Struct. Geol. 22: 1723–1735CrossRefGoogle Scholar
  20. Currey J D 1977 Mechanical properties of mother of pearl in tension.Proc. R. Soc. London B 196: 443–463Google Scholar
  21. Dameron C T, Rees R N, Mehra R K, Kortan A R, Carroll P J, Steiguwald M L, Brus L E, Winge D R 1989 Biosynthesis of cadmium sulphide quantum semiconductor crystallites.Nature (London) 338: 596–597CrossRefGoogle Scholar
  22. Daviss B 2000 Jet propelled tuna.New Scientist March: 36–40Google Scholar
  23. Desiraju G R 2001 Chemistry beyond the molecule.Nature (London) 397–400Google Scholar
  24. Dickinson M H 1999 Biological insight into mechanical design.Proc. Natl. Acad, Sci. USA 96:14208–209CrossRefGoogle Scholar
  25. Falini G, Albeck S, Weiner S, Addadi L 1996 Control of aragonite or calcite polymorphism by mollusk shell macromolecules.Science 271: 67–69CrossRefGoogle Scholar
  26. Funari S S, Rapp G 1999 A continuous topological change during phase transition in amphiphile/water systems.PINAS 96: 7756–7759CrossRefGoogle Scholar
  27. Jackson A P, Vincent J F V, Turner R M 1988 The mechanical design of nacre.Proc. R. Soc. London. B234: 415–440Google Scholar
  28. Klaus T, Joerger R, Olsson E, Granquist C-G 1999 Silver-based crystalline nanoparticles, microbially fabricated.Proc. Natl. Acid, Sci USA 24: 13611–13614CrossRefGoogle Scholar
  29. Klauss-Joerger T, Joerger R, Olsson E, Granquist C-G 2001 Bacteria as workers in the living factory: metal-accumulating bacteria and their potential for materials science.Trends BioTechnol. 19:15–20CrossRefGoogle Scholar
  30. Kuhu-Spearing L T, Kessler H, Spearing S M, Ballarini R, Heuer A H 1996 Fracture mechanisms of theStrombus gigas conch shell: Implications for the design of brittle laminates.J. Mater. Sci. 31: 6583–6594CrossRefGoogle Scholar
  31. Kresge C T, Leonowicz M E, Roth W J, Vartull J C, Beck J S 1992 Ordered mesoporous molecular sieves synthesized by a liquid-crystal template mechanism.Nature (London) 359: 710–712CrossRefGoogle Scholar
  32. Lakes R 1993 Materials with structural hierarchy.Nature (London) 361: 511–515CrossRefGoogle Scholar
  33. Lang S B 1966 Pyroelectric effect in bone and tendon.Nature (London) 212: 704–705CrossRefGoogle Scholar
  34. Levi C, Barton J L, Guillemet C, Le Bras E, Lehuede P 1989 A remarkably strong natural glassy rod: the anchoring spicule of the monorhaphis sponge.J. Mater. Sci. Lett. 8: 337–339CrossRefGoogle Scholar
  35. Mann S 1988 Molecular recognition in biomineralisation.Nature (London) 332: 119–124CrossRefGoogle Scholar
  36. Mann S 1993 Molecular tectonics in biomineralisation and biomimetic materials chemistry.Nature (London) 365: 499–505CrossRefGoogle Scholar
  37. Mann S (ed.) 1996Biomimetic materials chemistry (New York: VCH)Google Scholar
  38. Mann S, Hannington J P, Williams R J 1986 Phospholipid vesicles as a model system for biomineralisation.Nature (London) 324: 565–567CrossRefGoogle Scholar
  39. Mann S, Heywood B R, Rajam S, Birchall J D 1988 Controlled crystallisation of CaCÛ3 under stearic acid monolayers.Nature (London) 334: 692–695CrossRefGoogle Scholar
  40. Mann S, Archibald D D, Didymus J M, Douglas T, Heywood B R, Meldrum F C, Reeves N 1993 Crystallization at inorganic-organic interphases: Biominerals and biomimetic synthesis.Science 261: 1286–1292CrossRefGoogle Scholar
  41. Mattheick C 1994 Design in nature.Interdise. Sci. Rev. 19: 298–314Google Scholar
  42. Meadows R 1999 Designs from life.Zoogoer 28: 286–289Google Scholar
  43. Meldrum F C, Wade V J, Nimmo D L, Heywood B R, Mann S 1991 Synthesis of inorganic nanophase materials in supramolecular protein cages.Nature (London) 349: 684–687CrossRefGoogle Scholar
  44. Mendelson N H 1992 Production and initial characterisation of bionites: Materials formed on a bacterial backbone.Science 258: 1633–1636CrossRefGoogle Scholar
  45. Moskowitz B M 1995 Biomineralisation of magnetic minerals.Rev. Geophys. 33 (Suppl.): 123–128CrossRefGoogle Scholar
  46. Muthukumar M, Ober C K, Thomas E L 1997 Competing interactions and levels of ordering in self-organizing polymeric materials.Science 211: 1225–1232CrossRefGoogle Scholar
  47. Nayar S, Sinha A, Das S, Ramachandrarao P 2001In situ synthesis of nanosized cadmium sulfide particles in protein cages.J. Mater. Sci. Lett. 86: 357–359Google Scholar
  48. Rhee S-H, Tanaka J 2001 Synthesis of hydroxyapatitwe/collagen/chondroitin sulfate nanocomposite by a novel precipitation method.J. Am. Ceram. Soc. 84: 459–461CrossRefGoogle Scholar
  49. Sarikaya M 1999 Biomimetics: Materials fabrication through biology.Proc. Natl. Acad, Sci. USA 96: 14183–14185CrossRefGoogle Scholar
  50. Sellinger A, Weiss P M, Nguyen A, Lu Y, Assink R A, Gong W, Brinker C J 1998 Continuous self-assembly of organic-inorganic nanocomposite coatings that mimic nacre.Nature (London) 394: 256–260CrossRefGoogle Scholar
  51. Shilov A E 1996 InMetal complexes in biomimetic chemical reactions (New York: CRC Press)Google Scholar
  52. Sinha A, Das S K, Rao V, Ramachandrao P 2001a Patterning of polymeric surface by nanosized copper particles.J. Mater. Res. 46: 1846–1850Google Scholar
  53. Sinha A, Chakraborty J, Das S K, Rao V, Ramachandrao P 2001b Oriented array of nanocrystalline magnetite in polymeric matrix produced by biomimetic synthesis.Mater. Trans. J. Inst. Met. 42: 1672–1676CrossRefGoogle Scholar
  54. Smith B L, Schaeffer T E, Vlanl M, Thompson J B, Frederick N A, Klndt J, Belcher A, Stocky G D, Morse D E, Hansma P K 1999 Molecular mechanistic origin of the toughness of natural adhesives, fibres and composites.Nature (London) 399: 761–763CrossRefGoogle Scholar
  55. Stokroos I, Litinetsky L, Van der Want J J L, Ishay J S 2001 Keystone-like crystals in cells of hornet combs.Nature (London) 411: 654CrossRefGoogle Scholar
  56. Stopp S I, Braun P V 1997 Molecular manipulation of microstructures: Biomaterials, ceramics and semiconductors.Science 211: 17A1–1248Google Scholar
  57. Tas A C 2000 Synthesis of biomimetic Ca-hydroxyapatite powders at 37°C in synthetic body fluids.Biomaterials 21: 1429–1438CrossRefGoogle Scholar
  58. Thompson J B, Paloczi G T, Kindt J H, Michenfelder M, Smith B L, Stocky G, Morse D E, Hansma P K 2000 Direct observation of the transition from calcite to aragonite growth as induced by abalone shell proteins.Biophys. J. 79: 3307–3312CrossRefGoogle Scholar
  59. Thurn-Albrecht T Schotter J, Kastle G A, Emley N, Shibauchi T, Krusin-Elbaum L, Guarini K, Black C T, Tuominen M T, Russell T P 2000 Ultrahigh-density nanowire arrays grown in self assembled diblock copolymer templates.Science 290: 2126–2129CrossRefGoogle Scholar
  60. Triantafyllou M S, Triantafyllou G S 1995 An efficient swimming machine.Sci. Am. (3): 40–48Google Scholar
  61. Velv O D, Lenhoff A M, Kaler E W 2000 A class of micro structured particles through colloidal crystallisation.Science 287: 2240–2243CrossRefGoogle Scholar
  62. Vincent J F V 1997 Stealing ideas from nature.RSA J. August: 36–43Google Scholar
  63. Vincent J F V 2001 Ceramics from invertebrate animals. InHandbook of elastic properties of solids, liquids and gases, Volume 3: Elastic properties of solids: biological and organic materials, earth and marine sciences (New York: Academic Press)Google Scholar
  64. Walsh D, Hopwood J D, Mann S 1994 Crystal tectonics: Construction of reticulated calcium phosphate frameworks in bicontinuous reverse microemulsions.Science 264: 1576–1578CrossRefGoogle Scholar
  65. Wang R Z, Addadi L, Weiner S 1997 Design strategies of sea urchin teeth: structure, composition and micromechanical relations to function.Philos. Trans. R. Soc. London B352: 469–480Google Scholar
  66. Weiner S 1984Philos. Trans. R. Soc. London B304: 425Google Scholar
  67. Weiner S, Addadi L, Daniel, Wagner H 2000 Materials design in biology.Mat. Sci. Engg. C11: 1–8CrossRefGoogle Scholar
  68. Wootton R J 1990 The mechanical design of insect wings.Sci. Am. November: 66–72Google Scholar
  69. Zhou B L 1994 The biomimetic study of composite materials.J. Met. February: 57–62Google Scholar

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© Printed in India 2003

Authors and Affiliations

  • P. Ramachandra Rao
    • 1
  1. 1.Banaras Hindu UniversityVaranasiIndia

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