Development of a mathematical analysis method for the multicomponent separation by displacement development
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A simple mathematical method for the analysis of multicomponent displacement development was developed. Calculations in this method utilizes the information residing in the isotactic condition which is established after the full development of solute propagation occurring in the Chromatographie separation operated by the mode of displacement development. Transient shock wave velocities and concentration changes are determined based upon the equilibrium theory of chromatography and the basic rules required in constructing the (t,z)-diagram of solute propagation along the column. Calculations involve solving simple algebraic equations to predict the transient behaviors of propagating solutes inside the column, the elution profiles of final products, and the minimum column length required for the complete separation.
Key wordsChromatography Displacement Development Isotactic Condition Shock Wave Solute Propagation
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