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Journal of Biosciences

, Volume 11, Issue 1–4, pp 41–46 | Cite as

Oligosaccharide structure determination of glycoconjugates using lectins

  • Debkumar Basu
  • Jyotiv Nair
  • P. S. Appukuttan
Article

Abstract

Lectins, the divalent or polyvalent (glyco) proteins of non-immune origin of the cells agglutinate cells or other materials, that display more than one saccharide of sufficient complementarity. Lectins considered ‘identical’ in terms of mono-and disaccharide specificity can be differentiated by their ability to recognise the fine differences in more complex structures. The present review discusses the interaction of lectins with various oligosaccharides and their resultant separations due to structural variations.

Keywords

Oligosaccharide structures lectins glycoconjugates 

Abbreviations used

ConA

Concanavalin A

galNAc

N-acetyl galactosamine

gal

galactose

NeuAc

N-acetylneuraminic acid

man

mannose, Asn, asparagine

fuc

fucose

glc

glucose

glcNAc

N-acetyl gluco-samine

RCAI

Ricinus communis agglutinin

RCAII

R. communis toxin

WBA

Winged bean agglutinin

WGA

Wheat germ agglutinin

PHA

Phaseolus vulgaris

E-PHA

erythrocyte PHA

L-PHA

leucocyte PHA

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Copyright information

© Indian Academy of Sciences 1987

Authors and Affiliations

  • Debkumar Basu
    • 1
  • Jyotiv Nair
    • 1
  • P. S. Appukuttan
    • 1
  1. 1.Neurochemistry DepartmentSree Chitra Tirunal Institute for Medical Sciences and TechnologyTrivandrumIndia

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