Journal of Biosciences

, Volume 11, Issue 1–4, pp 41–46 | Cite as

Oligosaccharide structure determination of glycoconjugates using lectins

  • Debkumar Basu
  • Jyotiv Nair
  • P. S. Appukuttan


Lectins, the divalent or polyvalent (glyco) proteins of non-immune origin of the cells agglutinate cells or other materials, that display more than one saccharide of sufficient complementarity. Lectins considered ‘identical’ in terms of mono-and disaccharide specificity can be differentiated by their ability to recognise the fine differences in more complex structures. The present review discusses the interaction of lectins with various oligosaccharides and their resultant separations due to structural variations.


Oligosaccharide structures lectins glycoconjugates 

Abbreviations used


Concanavalin A


N-acetyl galactosamine




N-acetylneuraminic acid


mannose, Asn, asparagine






N-acetyl gluco-samine


Ricinus communis agglutinin


R. communis toxin


Winged bean agglutinin


Wheat germ agglutinin


Phaseolus vulgaris


erythrocyte PHA


leucocyte PHA


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Copyright information

© Indian Academy of Sciences 1987

Authors and Affiliations

  • Debkumar Basu
    • 1
  • Jyotiv Nair
    • 1
  • P. S. Appukuttan
    • 1
  1. 1.Neurochemistry DepartmentSree Chitra Tirunal Institute for Medical Sciences and TechnologyTrivandrumIndia

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