Abstract
Lectins, the divalent or polyvalent (glyco) proteins of non-immune origin of the cells agglutinate cells or other materials, that display more than one saccharide of sufficient complementarity. Lectins considered ‘identical’ in terms of mono-and disaccharide specificity can be differentiated by their ability to recognise the fine differences in more complex structures. The present review discusses the interaction of lectins with various oligosaccharides and their resultant separations due to structural variations.
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Abbreviations
- ConA:
-
Concanavalin A
- galNAc:
-
N-acetyl galactosamine
- gal:
-
galactose
- NeuAc:
-
N-acetylneuraminic acid
- man:
-
mannose, Asn, asparagine
- fuc:
-
fucose
- glc:
-
glucose
- glcNAc:
-
N-acetyl gluco-samine
- RCAI:
-
Ricinus communis agglutinin
- RCAII:
-
R. communis toxin
- WBA:
-
Winged bean agglutinin
- WGA:
-
Wheat germ agglutinin
- PHA:
-
Phaseolus vulgaris
- E-PHA:
-
erythrocyte PHA
- L-PHA:
-
leucocyte PHA
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Basu, D., Nair, J. & Appukuttan, P.S. Oligosaccharide structure determination of glycoconjugates using lectins. J. Biosci. 11, 41–46 (1987). https://doi.org/10.1007/BF02704656
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DOI: https://doi.org/10.1007/BF02704656