Journal of Biosciences

, Volume 15, Issue 3, pp 153–157 | Cite as

Peptide induced polymorphism in model membranes

  • Ratna S. Phadke
  • Sudha Srivastava
  • Girjesh Govil


Lipids in biological membranes generally adopt bilayer structures. However, incorporation of peptides may induce alterations in such structures. We have studied the influence of tryptophan, leucine, Trp-Leu, luteinizing hormone releasing hormone and renin inhibitor peptide on lipid organisation in liposomes. It has been observed that the effect is specific to the peptide molecule as-a whole and does not have direct correlation to the constituent amino acids or the conformation of the molecule.


Peptides phosphorous NMR polymorphism electron microscopy liposomes 

Abbreviations used


Electron spin resonance


dipalmytoyl phosphatidyl choline


chemical shift anisotropy


luteinizing hormone releasing hormone


renin inhibitor polypeptide


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Copyright information

© Indian Academy of Sciences 1990

Authors and Affiliations

  • Ratna S. Phadke
    • 1
  • Sudha Srivastava
    • 1
  • Girjesh Govil
    • 1
  1. 1.Chemical Physics GroupTata Institute of Fundamental ResearchBombayIndia

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