Journal of Biosciences

, Volume 3, Issue 2, pp 125–128 | Cite as

Localization of glucose-6-phosphatase and fructose-1-6-diphosphaiase in subcellular fractions from different regions of the rat brain

  • Gurucharan Kaur
  • Rameshwar Singh
  • N. Z. Baquer


Two key enzymes of gluconeogenesis, glucose-6-phosphatase and fructosp-1-6-diphosphatase, were present in the cerebral hemispheres, the cerebellum and the brain stem of the rat brain. Significant activities of these-enzymes were associated with the particulate fraction.


Glucose-6-phosphatase fructose-1–6-diphosphatase brain subcellular localization 


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  1. Ashmore, J. and Weber, G. (1959)Vitam. Horm.,17, 91.CrossRefGoogle Scholar
  2. Baginski, E. S., Piero, P. F. and Bennie Zak (1974)Methods of enzymatic analysis, ed. H. U. Bergmeyer (New York: Academic Press)2, 876.Google Scholar
  3. Balazs(1970)Handbook of neurochemistry, ed. A. Lajtha (New York: Plenum Press)3, 1.Google Scholar
  4. Chen, P. S. and Toribara, T. Y. and Warner, H. (1956)Anal. Chem.,28, 1756.CrossRefGoogle Scholar
  5. Cheng, S. C. and Cheng, R. H. C. (1972)Arch. Biochem. Biophys.,151, 501.PubMedCrossRefGoogle Scholar
  6. Exton, J. H. (1972)Metabolism,21, 945.PubMedCrossRefGoogle Scholar
  7. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951)J. Biol. Chem.,193, 265.PubMedGoogle Scholar
  8. MacDonnel, P. C. and Greengard, O, (1974)Arch. Biochem. Biophys.,163, 644.CrossRefGoogle Scholar
  9. Patel, M. S. (1974)J. Neurochem.,22, 717.PubMedCrossRefGoogle Scholar
  10. Richardson, R. J., Davis, C. S. and Johnson, M. K. (1979)J. Neurochem.,32, 607.PubMedCrossRefGoogle Scholar
  11. Tejwani, G. A., Pedrosa, F. O., Pontremoli. S. and Horecker, B. L. (1976)Arch. Biochem. Biophys.,177, 253.PubMedCrossRefGoogle Scholar
  12. Toshima, Y. and Yoshimura, N. (1975)J. Biol. Chem.,78, 1181.Google Scholar
  13. Vorhaben, J. E. and Campbell, J. W. (1979)Comp. Biochem. Physiol.,B62, 85.Google Scholar
  14. Whittaker, V. P. (1959)Biochem. J.,72, 694.PubMedGoogle Scholar

Copyright information

© Indian Academy of Sciences 1981

Authors and Affiliations

  • Gurucharan Kaur
    • 1
  • Rameshwar Singh
    • 1
  • N. Z. Baquer
    • 1
  1. 1.School of Life SciencesJawaharlal Nehru UniversityNew Delhi

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