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An experimental model of pseudotuberculosis infection in monkeys

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

An experimental model of pseudotuberculosis infection was developed usingPapio hamadryas monkeys. Clinical manifestations and some microbiological and immunological aspects of pseudotuberculosis caused by oral infection of animals are studied. The values of LD50 of the pseudotuberculosis agent are established for monkeys, white mice, and guinea pigs. Oral infection of monkeys with sublethal doses ofYersinia pseudotuberculosis is found to induce a pronounced specific immunity. The efficacy of immunoblotting for serologic diagnosis of pseudotuberculosis in clinically obscure cases is demonstrated.

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Authors and Affiliations

  1. Research Institute of Microbiology, Ministry of Defence of Russia, Kirov

    I. V. Marakulin, I. V. Darmov, I. P. Pogorel'skii, V. I. Drobkov & V. N. Pautov

Authors
  1. I. V. Marakulin
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  2. I. V. Darmov
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  3. I. P. Pogorel'skii
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  4. V. I. Drobkov
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  5. V. N. Pautov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 7, pp. 59–62, July, 1994

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Marakulin, I.V., Darmov, I.V., Pogorel'skii, I.P. et al. An experimental model of pseudotuberculosis infection in monkeys. Bull Exp Biol Med 118, 743–746 (1994). https://doi.org/10.1007/BF02444374

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  • DOI: https://doi.org/10.1007/BF02444374

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