Abstract
A numerical analysis of Newtonian and non-Newtonian flow in an axi-symmetric tube with a local constriction simulating a stenosed artery under steady and pulsatile flow conditions was carried out. Based on these results, the concentration fields of LDL (low-density lipoprotein) and Albumin were discussed. According to the results, in great details the macromolecule transport influences of wall shear stress, non-Newtonian fluid character and the scale of the molecule etc are given. The results of Newtonian fluid flow and non-Newtonian fluid flow, steady flow and pulsatile flow are compared. These investigations can provide much valuable information about the correlation between the flow properties, the macromolecule transport and the development of atherosclerosis.
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Communicated by Wu Wang-yi
Foundation item: the National Natural Science Foundation of China (19732003)
Biography: Li Xin-yu (1971-), Master
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Xin-yu, L., Gong-bi, W. & Ding, L. Computer simulation of non-Newtonian flow and mass transport through coronary arterial stenosis. Appl Math Mech 22, 409–424 (2001). https://doi.org/10.1007/BF02438307
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DOI: https://doi.org/10.1007/BF02438307