Abstract
Pediatric radiologists have made numerous and important contributions to the body of medical knowledge. This essay reviews aspects of biomedical and radiological research, analyses the state of scholarship in pediatric radiology today, and examines future research opportunities. The author's research interest in cardiopulmonary malformations and in the use of murine models of human disease serve to illustrate of but one of many investigative areas open to academic pediatric radiologists. Finally, the application process for NIH funding is briefly discussed.
Similar content being viewed by others
References
The Oxford English Dictionary (1933) Vol VIII, Oxford
Moser KM (1986) Research: What is it? ATS News Winter, 6
Lastrucci CL (1967) The scientific approach. Schenkman, Cambridge
Abrams HL (1981) Research in diagnostic radiology: A holistic perspective. Clin Radiol 32: 121
Caffey J (1956) The first sixty years of pediatric roentgenology in the United States — 1896–1956. AJR 76: 437
Kirkpatrick JA, Effmann EL, Brasch RC (1984) Pediatric radiology. Invest Radiol 19: S13
(1984) Plan for diagnostic imaging research: report of the task force report. Invest Radiol [Suppl] 19(3)
Taveras JM (1986) Subspecialization in radiology. What approach should we take? Invest Radiol 21: 91
Volpe JJ, Herscovitch P, Perlman JM, Raichle ME (1983) Positron emission tomography in the newborn: extensive impairment of regional cerebral blood flow with intraventricular hemorrhage and hemorrhagic intracerebral involvement. Pediatrics 72: 589
Birnholz JC, Farrell EE (1984) Ultrasound images of human fetal development. Am Sci 72: 608
Bone SN, Johnson GA, Thompson MB (1986) Three dimensional MR microscopy of the developing chick embryo. Invest Radiol 21: 782
Johnson GA, Thompson MB, Gewalt SL, Hayes CE (1986) Nuclear magnetic resonance imaging at microscopic resolution. J Mag Reson 68: 129
Hedlund L, Johnson GA, Karis J, Effmann EL (in press, 1986) Magnetic resonance microscopy of the rat thorax: cardiac gated, 3DFT imaging. J Comput Assist Tomogr
Buckle VJ (1984) Chromosome maps of man and mouse II. Clin Genet 26: 1
Effmann EL (1982) Development of the right and left pulmonary arteries — a micronagiographic study in the mouse. Invest Radiol 17: 529
Effmann EL (1983) New approaches to microangiography. In: Milne E, Higgins CB, James AE (eds): Models and techniques in medical imaging research. Praeger, New York, p 164
Effmann EL, Whitman SA (1984) Abnormal cardiovascular development in murine Trisomy 13. Circulation 70: 426
Pexieder T, Miyabara S, Gropp A (1981) Congenital heart disease in experimental (fetal) mouse trisomies: incidence. In: Perspectives in Cardiovascular Research, vol 5. Raven P, New York, p 389
Gropp A, Winking H, Herbst EW, Claussen CP (1983) Murine trisomy: developmental profiles of the embryo, and isolation of trisomic cellular systems. J Exp Zool 228: 253
Effmann EL, Whitman SA (1986) Cardiovascular defects in murine homozygous Splotch embryos. Teratology 34: 103
Green MC (ed) (1981) Genetic variants and strains of the laboratory mouse. Fischer, New York
Woychik RP, Stewart TA, Davis LG, D'Eustachio P, Leder P (1986) An inherited limb deformity created by insertional mutagenesis in a transgenic mouse. Nature 318: 36
Festing MFW (1979) Inbred strains in biomedical research. Macmillian Press, London
Andrews EJ, Ward BC, Altman, NH (eds) (1979) Spontaneous animal models of human disease, Vols I, II. Academic Press, New York
Eaves GN (1972) Who reads your project-grant application to the National Institutes of Health? Fed Proc 31: 2
Mandel HG (1983) Funding more NIH research grants. Science 221: 338
Devey GB (1985) The federal scene. Invest Radiol 20: 331
Hillman BJ (1985) The inadequacy in the number and quality of physician researchers. A perspective and approach to the problem. Invest Radiol 20: 767
Author information
Authors and Affiliations
Additional information
Address presented to the Society for Pediatric Radiology, Washington, D.C., 13 April 1986
Rights and permissions
About this article
Cite this article
Effmann, E.L. Research by pediatric radiologists — Past accomplishments and future opportunities. Pediatr Radiol 17, 355–361 (1987). https://doi.org/10.1007/BF02396607
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02396607