Pediatric Radiology

, Volume 18, Issue 1, pp 32–34 | Cite as

Hepatobiliary scintigraphy in arteriohepatic dysplasia (Alagille's syndrome)

A report of two cases
  • D. A. Summerville
  • M. Marks
  • S. T. Treves


Hepatobiliary scintigraphy has proven to be of great utility in distinguishing biliary atresia from other causes of neonatal cholestasis. Arteriohepatic dysplasia (Alagille's syndrome) is an uncommon entity characterized by typical facial features, pulmonary artery stenosis, and a liver disorder which presents during the neonatal period as progressive jaundice. Two neonates, who were later shown to have Alagille's syndrome, underwent hepatobiliary scintigraphy to rule out biliary atresia. Findings on the hepatobiliary scans from the two patients were similar to those usually associated with biliary atresia and both finally required surgical exploration to rule out biliary atresia. The findings on hepatobiliary scans in these patients with Alagille's syndrome are discussed and compared with those associated with other forms of neonatal cholestasis.


Public Health Pulmonary Artery Artery Stenosis Cholestasis Neonatal Period 
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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • D. A. Summerville
    • 1
  • M. Marks
    • 1
  • S. T. Treves
    • 1
  1. 1.Division of Nuclear Medicine Department of RadiologyThe Children's Hospital and Harvard Medical SchoolBostonUSA

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