Pediatric Radiology

, Volume 15, Issue 2, pp 144–146 | Cite as

Wolman's disease

Ultrasound and CT diagnosis
  • R. V. Dutton
Short Reports


An infant with the typical clinical and radiographic findings of Wolman's disease was also examined with ultrasound and CT. Although the radiographs are distinctive, the newer modalities add another dimension of examination.


Public Health Radiographic Finding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Wolman M, Sterk VV, Gatt S, Frenkel M (1961) Primary familial xanthomatosis with involvment and calcification of the adrenals: report of two more cases in siblings of a previously described infant. Pediatrics 28: 742PubMedGoogle Scholar
  2. 2.
    Abramov A, Schorr S, Wolman M (1956) Generalized xanthomatosis with calcified adrenals. Am J Dis Child 91: 282Google Scholar
  3. 3.
    Assman G, Frederickson D (1983) Acid lipase deficiency: Wolman's disease and cholesteryl ester storage disease. In: Stanbury JB, Wyngaarden JB, Fredrickson DS, Goldstein J, Brown M (eds) The metabolic basis of inherited disease, 5th ed. McGraw-Hill, New York p 803Google Scholar
  4. 4.
    Beaudet AL, Pediatric genetics laboratory, Baylor College of Medicine (personal communication)Google Scholar
  5. 5.
    Beaudet A, Lipson M, Ferry G, Nichols B (1974) Acid lipase in cultured fibroblasts: cholesterol ester storage disease. J Lab Clin Med 84: 54PubMedGoogle Scholar
  6. 6.
    Queloz J, Capitanio M, Kirkpatrick J, Wolman's disease (1972) Roentgen observations in three siblings. Radiology 104: 357PubMedGoogle Scholar
  7. 7.
    Harrison R, Capitanio M, Kirkpatrick J (1977) Radiographic findings in Wolman's disease. Radiology 124Google Scholar
  8. 8.
    Hill S, Hoeg J, Dwyer A, Vuciek J, Doppman J (1983) CT findings in acid lipase deficiency: Wolman's disease and cholesteryl ester storage disease. J Comput Assist Tomogr 7: 815PubMedGoogle Scholar
  9. 9.
    Yeh HC (1980) Sonography of the adrenal glands: normal glands and small masses. AJR 135: 1167PubMedGoogle Scholar
  10. 10.
    Schaub J, Janka GE, Christomanou H, Sandhoff K, Permanetter W, Hübner G, Meister P (1980) Wolman's disease: clinical, biochemical and ultrastructural studies in an unusual case without striking adrenal calcifications. Eur J Pediatr 135: 45CrossRefPubMedGoogle Scholar
  11. 11.
    Bambierra E, Tafura W, Borges H, Carvalho C, Naves I, Bogliolo L, Tafuri C, Mirand D (1982) Wolman's disease: clinicopathologic, electron microscopic, and histochemical study. SMJ 75: 595Google Scholar

Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • R. V. Dutton
    • 1
  1. 1.Department of Radiology Baylor College of MedicineTexas Children's HospitalHoustonUSA

Personalised recommendations