Abstract
Eight children representing a spectrum of clinical states of biopsy-proven Duchenne muscular dystrophy (DMD) underwent magnetic resonance (MR) scans to assess the degree of muscular involvement and disease progression. Five muscle groups (neck, shoulder girdle, pelvic girdle, thigh and calf) were evaluated. In each case, involved muscles were clearly demarcated. Image estimates of disease severity by degree of muscle involvement correlated well with clinical staging. In our experience MR is useful for assessment of disease stage, selection of appropriate muscles for biopsy and planning for courses of physical and rehabilitation therapy.
This is a preview of subscription content, log in via an institution to check access.
References
Brown RG, Ash JM, Verellen-Dumoulin C, Precy ME, Chang LS, Oss I, Fulford P (1981) Gallium-67 citrate localization in carriers of Duchenne muscular dystrophy. Int J Nucl Med Biol 8: 379
Bulcke JA, Crolla D, Termote JL, Baert A, Palmers Y, Van den Bergh R (1981) Computed tomography of muscle. Muscle Nerve 4: 67
Cady EB, Gardener JE, Edwards RMT (1983) Ultrasonic characterization of skeletal muscle. Eur J Clin Invest 13: 469
Hanson RJ, Zellweger H (1968) The muscular dystrophies in Iowa. J Iowa Med Soc 58: 251
Hawley RJ, Schellinger D, O'Doherty S (1984) Computed tonographic patterns of muscle in neuromuscular disease. Arch Neurol 41: 383
Heckmatt JZ, Leeman S, Dubowitz B (1982) Ultrasound imaging in the diagnosis of muscle disease. J Pediatr 101 (5): 656
Jiddane M, Gastaut JL, Pellissier JF, Pouget J, Serratrice G, Salamon G (1983) CT of primary muscle disease. AJNR 4 (3): 773
Moon KL, Tenant HK, Helms CA, Chafetz NI, Crooks LE, Kaufman C (1983) Musculoskeletal applications of nuclear magnetic resonance. Radiology 147: 161
Riddlesberger MM (1981) Computed tomography of the musculoskeletal system. Radiol Clin North Am 19 (3): 463
Zellweger H, Hanson JW (1967) Psychometric studies in muscular dystrophy type IIIa (Duchenne). Dev Med Child Neurol 9 (5): 576
Radda GK, Bore PS, Rajogopolan B (1983) Clinical aspects of31P NMR spectroscopy. Br Med Bull 40 (2): 155
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Schreiber, A., Smith, W.L., Ionasescu, V. et al. Magnetic resonance imaging of children with Duchenne muscular dystrophy. Pediatr Radiol 17, 495–497 (1987). https://doi.org/10.1007/BF02388288
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02388288