Abstract
Changes of portal venous hemodynamics were investigated in 32 patients with cystic fibrosis (CF) with a mean age of 11.6 years. Hepatic profile of these patients included total bilirubin and albumin together with determination of size and echogenicity of the liver and spleen, determination of the diameter of the portal vein by real-time sonography and quantitation of flow volume of the portal vein using Duplex Doppler sonography. As a control, 35 age matched healthy children were also examined. Diameter of the portal vein was significantly increased in CF patients versus controls. Comparison of the mean flow volume of the portal vein showed a significant increase in CF-patients over 12 y old versus controls. In patients less than 12 y no significant difference of flow volume of the portal vein between CF-patients and controls was noted. The increase of diameter and flow volume of the portal vein suggest an adaptive mechanism in the pressure-volume relationship of the portal venous system in patients with CF.
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References
Willi UV, Reddish JM, Littlewood H, Teele R (1980) Cystic fibrosis: its characteristic appearance on abdominal sonography. AJR 134: 1005
Richardson PDI, Withrington PG (1981) Liver blood flow I. Intrinsic and nervous control of liver blood flow. Gastroenterology 81: 159
Ohnishi K, Saito M, Nakayama T, Iida S, Nomura F, Koen H, Okuda K (1985) Portal venous hemodynamics in chronic liver disease: effects of posture change and exercise. Radiology 155: 757
Patriquin H, Lafortune M, Burns PN, Dauzat M (1987) Duplex Doppler examination in portal hypertension: technique and anatomy. AJR 149: 71
Child CG, Turcotte JG (1964) Surgery and portal hypertension. In: Child CG (ed) The liver and portal hypertension. Saunders, Philadelphia, pp 50–56
Dittrich M, Milde S, Dinkel E, Baumann W, Weitzel D (1983) Sonographic biometry of liver and spleen size in childhood. Pediatr Radiol 13: 206
Niederau C, Sonnenberg A, Müller JE, Eickenbrecht JF, Scholten T, Fritsch WP (1983) Sonographic measurements of the normal liver, spleen, pancreas and portal vein. Radiology 149: 537
Taylor KJW, Carpenter DA, Hill CR, McCready VR (1976) Gray scale ultrasound imaging. The anatomy and pathology of the liver. Radiology 119: 415
Ohnishi K, Saito M, Koen H, Nakayama T, Nomura F, Okuda K (1985) Pulsed Doppler flow as a criterion of portal venous velocity: comparison with cineangiographic measurements. Radiology 154: 495
Moriyashu F, Nishida J, Ban N, Nakamura T, Sakai M, Miyake T, Uchino H (1986) “Congestion index” of the portal vein. AJR 146: 735
Sato S, Ohnishi K, Sugita S, Okuda K (1987) Splenic artery and superior mesenteric artery blood flow: Non surgical Doppler US measurement in healthy subjects and patients with chronic liver disease. Radiology 164: 347
Bolondi L, Gandolfi L, Arienti V, Caletti GC, Corcioni E, Gasbarrini G, Labo G (1982) Ultrasonography in the diagnosis of portal hypertension: diminished response of portal vessels to respiration. Radiology 142: 167
Moon YM, Kim DS, Choi HJ (1985) A study of the correlationship between the size of portal vein by ultrasonography and the wedged hepatic venous pressure in liver cirrhosis. In: Gill RW, Dadd MJ (eds) Proceedings of the Fourth Meeting of the World Federation for Ultrasound in Medicine and biology, Sydney, p 107
Viamonte Jr M, Danner P, Warren WD, Fomon J (1970) A new technique for the assessment of hyperkinetic portal hypertension. Radiology 96: 539
Moss AJ (1982) The cardiovascular system in cystic fibrosis. Pediatrics 5: 728
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Vergesslich, K.A., Götz, M., Mostbeck, G. et al. Portal venous blood flow in cystic fibrosis: assessment by Duplex Doppler sonography. Pediatr Radiol 19, 371–374 (1989). https://doi.org/10.1007/BF02387630
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DOI: https://doi.org/10.1007/BF02387630