Pharmaceutisch Weekblad

, Volume 5, Issue 5, pp 234–238 | Cite as

Alkaloids in ergot found on different Gramineae in The Netherlands

  • A. Reicher
  • E. T. Elema
  • J. H. Zwaving
  • Th. M. Malingré
Original Articles


The alkaloid content and the composition of the alkaloid complex of thirteen samples of ergot sclerotia from different gramineous host species collected in The Netherlands were investigated. Two samples collected in France were also examined. Ergot ofGlyceria fluitans (L.) R.Br. did not contain alkaloids. The total alkaloid content of ergot found on the other wild grasses was more than 0.2%. The ratio between the contents of water soluble and water insoluble alkaloids of the investigated ergot sclerotia varies between 1∶10 and 1∶20. The composition of the alkaloid complex in the sclerotia was studied by quantitative thin-layer chromatography. The sclerotia could be grouped into three main categories:
  • sclerotia ofLolium perenne L.,Festuca arundinacea Schreb. andArrhenatherum elatius (L.) P.B. ex J. et C. Presl, containing predominantly ergocornine, α- and β-ergokryptine and ergosine;

  • sclerotia ofDactylis glomerata L.,Phalaris arundinacea L.,Alopecurus geniculatus L. andHolcus mollis L., containing predominantly ergosine, ergocristine and ergotamine;

  • sclerotia ofMolinia caerulea (L.) Moench, containing predominantly ergocristine, ergosine and ergqmetrine.

A great similarity was found between the composition of the alkaloid complex in ergot ofLolium perenne L. from different locations and also in ergot ofMolinia caerulea (L.) Moench from different locations. This similarity was less in ergot ofDactylis glomerata L. collected from different locations.


Internal Medicine Alkaloid Host Species Main Category Great Similarity 
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Copyright information

© Bohn, Scheltema & Holkema 1983

Authors and Affiliations

  • A. Reicher
    • 1
  • E. T. Elema
    • 1
  • J. H. Zwaving
    • 1
  • Th. M. Malingré
    • 1
  1. 1.Laboratory of PharmacognosyState University of GroningenAW GroningenThe Netherlands

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