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Reaction of arylidene derivatives of Meldrum's acid with 3-amino-1,2,4-triazole

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The condensation of arylidene derivatives of Meldrum's acid with 3-amino-1,2,4-triazole in nitrobenzene leads to 4,5,6,7-tetrahydro-1,2,4-triazolo [1,5-a]pyrimidin-5-ones. In DMF the reaction proceeds with the formation of arylsubstituted N-(2H-1,2,4-triazol-3-yl)-3-(2H-1,2,4-triazol-3-ylamino)propionamides.

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Ukrainian Research Institute for the Pharmacotherapy of Endocrine Diseases, Kharkov 310002. Kharkov State University, Kharkov 310077, Ukraine

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Lipson, V.V., Orlov, V.D., Desenko, S.M. et al. Reaction of arylidene derivatives of Meldrum's acid with 3-amino-1,2,4-triazole. Chem Heterocycl Compd 35, 595–599 (1999). https://doi.org/10.1007/BF02324645

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  • DOI: https://doi.org/10.1007/BF02324645

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