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Synthesis and some properties of 6-(ω-aroylbutylthio)purines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A series of 6-(ω-aroylthio)purines, which have not been described in the literature, has been obtained by the reaction of 6-purinethione with ω-chlorovalerophenone and its substituted derivatives. Some properties of the compounds synthesized have been studied, viz. reaction at the carbonyl group, methylation, and hydrolysis.

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References

  1. E. V. Kochergina, A. N. Krasovskii, N. A. Klyuev, and V. V. Zamurenko,Farmats. Zh., No. 6, 33 (1981).

    Google Scholar 

  2. E. V. Aleksandrova, A. N. Krasovskii, and N. A. Klyuev,Abstracts of the III conference on Organic Chemistry and Technology, Moscow (1982), p. 86.

  3. P. M. Kochergin, M. Yu. Gromov, E. V. Aleksandrova, and S. Ya. Skachilova,Khim. Geterotsikl. Soedin., No. 11, 1548 (1993).

    Google Scholar 

  4. H. Gunther,Introduction to a Course on NMR Spectroscopy [Russian translation], Mir, Moscow (1984), p. 478.

    Google Scholar 

  5. M. V. Rubtsov and A. G. Baichinov,Synthetic Pharmaceutical Chemistry Prepations [in Russian], Meditsina, Moscow (1971), p. 280.

    Google Scholar 

  6. H. Normant and O. Varenix,Compt. Rend.,231, 703 (1950).

    CAS  Google Scholar 

  7. N. K. Zheltukhin, I. A. Tubasheva, E. Ya. Borisova, and S. Ya. Skachilova,Express Information. Series “Foremost Experience in the Pharmaceutical Chemistry Industry”, TsBNTI Medprom, Moscow (1986), p. 6.

    Google Scholar 

  8. E. Fischer, Chem. Ber.,31, 114 (1898).

    Google Scholar 

  9. Aldrich Calalog. Handbook of Fine Chemicals, 1992–1993, p. 719.

  10. G. B. Elion, E. Burgi, and G. H. Hitching,J. Am. Chem. Soc.,74, 411 (1952).

    CAS  Google Scholar 

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Authors
  1. M. Yu. Gromov
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  2. S. Ya. Skachilova
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  3. E. V. Aleksandrova
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  4. P. M. Kochergin
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Additional information

All-Russian Scientific Center for the Safety of Biologically Active Substances, Staraya Kupavna, Moscow region 142450. Zaporozhe State Medical University, Zaporozhe 330074, Ukraine. Center for Drug Chemistry, All-Russian Pharmaceutical Chemistry Research Institute, Moscow 119815. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1407–1411, October, 1999.

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Gromov, M.Y., Skachilova, S.Y., Aleksandrova, E.V. et al. Synthesis and some properties of 6-(ω-aroylbutylthio)purines. Chem Heterocycl Compd 35, 1225–1229 (1999). https://doi.org/10.1007/BF02323383

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  • DOI: https://doi.org/10.1007/BF02323383

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