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N-alkylation of trimethylsilyl derivatives of isatin with halomethyl ketones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Trimethylsilyl derivative of isatin react with halomethyl ketones at the nitrogen atom in contrast to sodium salt of isatin, which reacts with these compounds at heterocyclic carbon atom.

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References

  1. G. I. Zhungietu, V. I. Gorgos, N. A. Rekhter, and A. I. Korpan',Izv. Akad. Nauk MoldavSSR, Ser. Biol. Khim. Nauk, No. 3, 61 (1980).

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  2. M. A. Rekhter,Khim. Geterotsikl. Soedin, No. 9, 1170 (1998).

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  3. G. I. Zhungietu and M. A. Rekhter,Isatin and Its Derivatives [in Russian], Shtinitsa, Kishinev (1977), p. 33.

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Authors
  1. M. A. Rekhter
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Additional information

Institute for the Biological Protection of Vegetation, Academy of Sciences of Moldova, 2058, Moldova. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1345–1346, October, 1999.

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Rekhter, M.A. N-alkylation of trimethylsilyl derivatives of isatin with halomethyl ketones. Chem Heterocycl Compd 35, 1165–1166 (1999). https://doi.org/10.1007/BF02323373

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  • DOI: https://doi.org/10.1007/BF02323373

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