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Synthesis of 2-cyanomethylazaheterocycles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-(α-Aryloxyacetyl)cyanomethyl-, 2-(α-1-adamantylacetyl)cyanomethyl-, 2-(α-adamantoyl)cyanometyl-, and 2-(α-1-naphthylacetyl)cyanomethylazaheterocycles have been synthesized by treating 2-cyanomethylazaheterocycles with carboxylic acid chlorides. The 2-cyanomethylbenzimidazoles exist in the enaminoketone form. The biological activity of the synthesized compounds was studied and substances possessing fungicidal activity discovered.

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References

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T. G. Shevchenko University, Kiev 252033. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 520–522, April, 1997.

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Volovenko, Y.M., Blyumin, E.V., Shokol, T.V. et al. Synthesis of 2-cyanomethylazaheterocycles. Chem Heterocycl Compd 33, 445–447 (1997). https://doi.org/10.1007/BF02321390

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  • DOI: https://doi.org/10.1007/BF02321390

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