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Chemistry of Heterocyclic Compounds

, Volume 33, Issue 4, pp 441–444 | Cite as

1- and 2-(4-Hydroxycarbonylphenyl)-4-oxo-4,5,6,7-tetrahydroindazoles

  • A. Ya. Strakov
  • N. N. Tonkikh
  • M. V. Petrova
  • I. A. Strakova
Article

Abstract

Reactions of 4-hydrazinobenzoic acid with 2-formyl- and 2-acetyldimedones were utilized to synthesize 6,6-dimethyl- and 3,6,6-trimethyl-1-(4-hydroxycarbonylphenyl)-4-oxo-4,5,6,7-tetrahydroindazoles corre-spondingly, and the reaction with 2-cyano-3-ethoxy-5,5-dimethylcyclohex-2-en-1-one gave 2-(4-hydroxy-carbonylphenyl)-3-amino-4-oxo-6,6-dimethyl-4,5,6,7-tetrahydroindazole.

Keywords

Organic Chemistry Tetrahydroindazoles 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    V. Kumar, M. R. Bell, J. R. Wetzel, J. L. Herrmann, R. McGarry, H. P. Schane, R. C. Winneker, B. W. Snyder, and A. J. Anzalone, J. Med. Chem.36, 3278 (1993).Google Scholar
  2. 2.
    C. Ta-shue and C. Ruei-Chih, J. Org. Chem.,58, 493 (1993).Google Scholar
  3. 3.
    Ch. Kashima, I. Fukuchi, K. Takahashi, and A. Hosomi, Tetrahedron Lett.,34, 8305 (1993).CrossRefGoogle Scholar
  4. 4.
    U. Wrzeciono, E. Linkowska, K. Majewska, A. Gzella, and K. Stochla, Pharmazie,48, 852 (1993).Google Scholar
  5. 5.
    A. A. Bilgin, A. Yesilada, E. Palaska, and R. Sunal, Arzneimittel-Forsch.,42, 1271 (1992).Google Scholar
  6. 6.
    I. A. Strakova, A. Ya. Strakov, and M. V. Petrova, Khim. Geterotsikl. Soedin., No. 3, 351 (1995).Google Scholar
  7. 7.
    A. Ya. Strakov, M. V. Petrova, Yu. Yu. Popelis, A. A. Krasnova, and I. A. Strakova, Khim. Geterotsikl. Soedin., No. 2, 247 (1996).Google Scholar
  8. 8.
    A. Ya. Strakov, I. A. Strakova, and M. V. Petrova, Khim. Geterotsikl. Soedin., No. 5, 708 (1996).Google Scholar
  9. 9.
    I. A. Strakova, A. Ya. Strakov, and M. V. Petrova, Khim. Geterotsikl. Soedin., No. 4, 497 (1996).Google Scholar
  10. 10.
    A. Ya. Strakov, Yu. B. Sliede, M. V. Petrova, A. F. Mishnev, and A. A. Kemme, Khim. Geterotsikl. Soedin., No. 4, 501 (1996).Google Scholar
  11. 11.
    A. A. Akhrem, A. M. Moiseenkov, M. B. Andaburskaya, and A. Ya. Strakov, Izv. Akad. Nauk Latv., Ser. Khim., No. 6, 740 (1970).Google Scholar
  12. 12.
    A. Ya. Strakov, N. N. Tonkikh, and M. V. Petrova, Latv. Kim. Zurn., No. 2, 168 (1991).Google Scholar
  13. 13.
    A. Ya. Strakov, N. N. Tonkikh, K. Ya. Sedlenieks, and M. V. Petrova, Latv. Kim. Zurn., No. 1, 116 (1993).Google Scholar
  14. 14.
    N. N. Tonkikh, A. Ya. Strakov, and M. V. Petrova, Latv. Kim. Zurn., No. 4, 481 (1994).Google Scholar
  15. 15.
    A. Ya. Strakov, M. V. Petrova, A. Dishs, Yu. Popelis, and N. N. Tonkikh, Khim. Geterotsikl. Soedin., No. 2, 234 (1997).Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • A. Ya. Strakov
  • N. N. Tonkikh
  • M. V. Petrova
  • I. A. Strakova

There are no affiliations available

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