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Reaction of functionally 4-substituted hexahydropyrimidine-2-thiones with sodium tetrahydroborate. Synthesis of six-membered cyclic thioureas

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A new method was developed for the production of six-membered cyclic ureas based on the reaction of readily obtainable 4-azido-, 4-acetoxy-, or 4-phenylsulfonylhexahydropyrimidine-2-thiones with sodium tetrahydroborate.

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Authors
  1. A. D. Shutalev
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M. V. Lomonosov State Academy of Fine Chemical Technology, Moscow. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2. pp. 229–231, February. 1998.

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Shutalev, A.D. Reaction of functionally 4-substituted hexahydropyrimidine-2-thiones with sodium tetrahydroborate. Synthesis of six-membered cyclic thioureas. Chem Heterocycl Compd 34, 204–206 (1998). https://doi.org/10.1007/BF02315185

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  • DOI: https://doi.org/10.1007/BF02315185

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