Chemistry of Heterocyclic Compounds

, Volume 33, Issue 5, pp 583–586 | Cite as

Synthesis and properties of N-methylmorpholinium 6-methyl-4-(4-pyridyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate

  • S. G. Krivokolysko
  • V. D. Dyachenko
  • V. P. Litvinov


Condensation of acetoacetic acid anilide, 4-pyridyl aldehyde, cyanothioacetamide and N-methylmorpholine gave N-methylmorpholinium 6-methyl-4-(4-pyridyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate from which were obtained the corresponding substituted pyridinethiones, 2-alkylthio-1,4-dihydropyridines and 3-amino-2-benzoyl-6-methyl-4-(4-pyridyl)-5-phenylcarbamoylthieno[2,3-b]pyridine.


Organic Chemistry Aldehyde Pyridine Dihydropyridines Anilide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    H. Landmann and H. Lowe, Pharmazie,41, 169 (1986).Google Scholar
  2. 2.
    V. Handfeld, S. Leistner, D. Lohmann, H. Poppe, and S. Heer, Pharmazie,44, 12 (1989).Google Scholar
  3. 3.
    Kh. Okusima, A. Narimanu, and N. Simokota, Jpn. Pat. 58-15914; Ref. Zh. Khim., 12O117P (1984).Google Scholar
  4. 4.
    A. Rumler, V. Hagen, A. Hagen, Pharmazie,45, 657 (1990).Google Scholar
  5. 5.
    E. Klauschenz, V. Hagen, A. Hagen, and S. Heer, Pharmazie,45, 628 (1990).Google Scholar
  6. 6.
    A. Krauze and G. Duburs, Latv. Kim. Z., No. 1, 928 (1994).Google Scholar
  7. 7.
    A. A. Krauze, É. É. Liepin'sh, Yu. É. Pelcher, Z. A. Kalme, and G. Ya. Dubur, Khim. Geterotsikl. Soedin., No. 5, 630 (1986).Google Scholar
  8. 8.
    V. Hagen, E. Klauschenz, A. Rumler, A. Hagen, S. Heer, R. Mitzner, H. Niedrich, and D. Lohmann, Pharmazie,45, 189 (1990).Google Scholar
  9. 9.
    V. Hagen, A. Rumler, G. Reck, A. Hagen, D. Labes, and S. Herr, Pharmazie,44, 809 (1989).Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • S. G. Krivokolysko
  • V. D. Dyachenko
  • V. P. Litvinov

There are no affiliations available

Personalised recommendations