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Chemistry of Heterocyclic Compounds

, Volume 33, Issue 5, pp 577–582 | Cite as

Synthesis of N-methylmorpholinium 6-methyl-4-(2-thienyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate and its reaction with various functionally substituted methyl halides

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. P. Litvinov
Article

Abstract

Condensation of the anilide of acetoacetic acid, thiophene aldehyde, cyanothioacetamide and N-methyl-morpholine gave N-methylmorpholinium 6-methyl-4-(2-thienyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate which reacted with various halides ZCH2Hal or H2NCOCH(Ph)Cl to give substituted 2-ZCH2-thio or 2-H2NCOCH(Ph)-thio-1,4-dihydropyridines.

Keywords

Methyl Organic Chemistry Aldehyde Thiophene Halide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    V. V. Kastron, R. O. Vitolinya, and G. Ya. Dubur, Khim-Farm. Zh., No. 6, 14 (1990).Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. P. Litvinov

There are no affiliations available

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