Chemistry of Heterocyclic Compounds

, Volume 33, Issue 12, pp 1430–1437 | Cite as

Synthesis of 4-alkyl-6-amino-3,5-dicyano-2(1H)-pyridinethiones

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. N. Nesterov
  • V. P. Litvinov


Condensation of aliphatic aldehydes with cyanothioacetamide has given 4-alkyl-6-amino-3,5-dicyano-2(1H)-pyridinethiones, which have also been synthesized by recyclization of 4-alkyl-2,6-diamino-4H-thiopyrans. Substituted 2-alkylthiopyridines and thieno[2,3-b]pyridines have been prepared from the pyridinethiones. 2,6-Diamino-4-isopropyl-3,5-dicyano-4H-thiopyran and 6-amino-4-isobutyl-2-methylthio-3,5-dicyanopyridine have been studied by x-ray crystallography.


Organic Chemistry Aldehyde Pyridine Aliphatic Aldehyde Cyanothioacetamide 
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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. N. Nesterov
  • V. P. Litvinov

There are no affiliations available

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