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Investigation of the oxidation-reduction transformations of derivatives of dipyrimido-[4,5-b][4′,5′-e][1,4]thiazine

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The oxidation-reduction characteristics of both the free radical and the reduced forms of dipyrimido[4,5-b][4′,5′-e][1,4]thiazine derivatives were studied by polarography. It was found that these compounds can participate in oxidation-reduction reactions, such as the oxidation of thiols and ascorbic acid (the radical form) and the reduction of oxygen (the reduced from). This makes it possible to regard them as a system capable of modelling certain oxidation-reduction processes that take place in the living organism.

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Authors
  1. M. P. Nemeryuk
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  2. N. B. Grigor'ev
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  3. N. I. Traven'
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  4. V. I. Levina
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  5. E. V. Dekhtyarev
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  6. T. S. Safonova
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Additional information

Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1398–1401, October, 1997.

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Nemeryuk, M.P., Grigor'ev, N.B., Traven', N.I. et al. Investigation of the oxidation-reduction transformations of derivatives of dipyrimido-[4,5-b][4′,5′-e][1,4]thiazine. Chem Heterocycl Compd 33, 1215–1218 (1997). https://doi.org/10.1007/BF02290873

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  • DOI: https://doi.org/10.1007/BF02290873

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