Skip to main content
SpringerLink
Log in

Synthesis and reactions of 2-(4-pyridyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazoline

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

7,7-Dimethyl- and 7-phenyl-2-(4-pyridyl)-5-oxo-5,6,7,8-tetrahydroquinazolines were synthesized in the reactions of 2-formyl-5,5-dimethyl- and 5-phenyl-1,3-cyclohexanediones, respectively, with 4-amidinopyridine. The oxime, thiosemicarbazone, 4-quinazolyl-, nicotinoyl-, isonicotinoyl-, and 2-hydroxybenzoylhydrazones of 2-(4-pyridyl)-5-oxo-7,7-dimethyl-5,6,7,8-tetrahydroquinazoline were obtained. The reduction of this ketone by sodium borohydride leads to the 5-hydroxy derivative.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. D. V. Brutane and A. Ya. Strakov, Izv. Akad. Nauk LatvSSR, Ser. Khim., No. 2, 202 (1970).

    Google Scholar 

  2. D. V. Brutane, A. Ya. Strakov, and I. A. Strakova, Izv. Akad. Nauk LatvSSR, Ser. Khim., No. 4, 485 (1970).

    Google Scholar 

  3. A. Ya. Strakov, D. V. Brutane, A. M. Moiseenkov, and A. A. Akhrem, Izv. Akad. Nauk LatvSSR, Ser. Khim., No. 5, 610 (1970).

    Google Scholar 

  4. A. Ya. Strakov, T. F. Kozlovskaya, M. V. Petrova, and R. G. Tkachenko, Izv. Akad. Nauk Latv, Ser. Khim., No. 5, 579 (1989).

    Google Scholar 

  5. A. Ya. Strakov, M. V. Petrova, Yu. Popelis, A. A. Krasnova, and I. A. Strakova, Khim. Geterotsikl. Soedin., No. 2, 247 (1996).

    Google Scholar 

Download references

Authors
  1. N. N. Tonkikh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Ya. Strakov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. V. Petrova
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Riga Technical University, Riga LV-1658, Latvia, e-mail: marina@osi.lanet.lv. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 101–103, January, 1998.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tonkikh, N.N., Strakov, A.Y. & Petrova, M.V. Synthesis and reactions of 2-(4-pyridyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazoline. Chem Heterocycl Compd 34, 92–95 (1998). https://doi.org/10.1007/BF02290618

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02290618

Keywords

Search

Navigation