Abstract
We have shown that as a result of reaction of phenylisocyanate with 2-benzyl- and 2-aryliminohexahydrothiazepines, the corresponding N-substituted N-tetrahydroazepinyl-N′-phenylureas are formed. In the case of isothiocyanates, on boiling in different solvents we obtained the products of the exchange reaction; and at room temperature, we also obtained substituted thioureas. We suggest a probable scheme for the process.
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References
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Additional information
For communication 1, see [1].
Institute of Phytochemistry, Academy of Sciences of the Uzbekistan Republic, Tashkent 700170. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 416–422, March, 1997.
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Ambartsumova, R.F., Levkovich, M.G. & Abdullaev, N.D. 1,3-thiazepines. 2. Reaction of 2-iminohexahydrothiazepines with phenylisocyanate and isothiocyanates. Chem Heterocycl Compd 33, 355–360 (1997). https://doi.org/10.1007/BF02253119
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DOI: https://doi.org/10.1007/BF02253119