Abstract
By the interaction of substituted chloropyrimidines with the sodium salts of oximes of aliphatic and alicyclic ketoximes, series of O-(4,6-dimethyl-2-pyrimidinyl)- and O-(2,4-dimethyl-6-pyrimidyl)ketoximes have been obtained. Through reactions of 2-methyl-4,6-dichloropyrimidine with salts of ketoximes, the corresponding monosubstituted and disubstituted products have been synthesized. The biological activities of the synthesized substances have been investigated.
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References
G. G. Danagulyan, N. G. Balasanyan, P. B. Terent'ev and M. G. Zalinyan, Khim. Geterotsikl. Soedin., No. 12, 1644 (1989).
P. B. Terent'ev (Terentiev), A. N. Kost, and J. Lange, Org. Mass Spectrom.,9, 1022 (1974).
J. D. Hennion and D. G. J. Kingston, Org. Mass Spectrom.,13, 431 (1978).
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Erevan Institute of the National Economy, Erevan 375025. M. V. Lomonosov Moscow State University, Moscow 119899. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 950–956, July, 1997.
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Danagulyan, G.G., Balasanyan, N.G., Zalinyan, M.G. et al. Synthesis and biological activity of certain O-pyrimidinylketoximes. Chem Heterocycl Compd 33, 831–837 (1997). https://doi.org/10.1007/BF02253035
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DOI: https://doi.org/10.1007/BF02253035