Abstract
The reaction of 3-isothiocyanatobutanal with ethanol in the presence of ethyl orthoformate produced 1,1-diethoxy-3-isothiocyanatobutane. The latter was used to devise methods of preparing 3-methylaminobutanal diethylacetal, N-(4-diethoxybutyl-2)thioamides, N-(4-oxybutyl-2)-thioamides, and 6-methyl-3-phenyl-5,6-dihydropyridine-2(1H)-thione.
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Omsk State University, Omsk 644077. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 921–927, July, 1997.
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Fisyuk, A.S., Berdovich, L.V., Temnikov, D.V. et al. N-3-oxoalkylamides and-thioamide in the synthesis of heterocyclic compounds. Part 1. Synthesis of 1,1-diethoxy-3-isothiocyanatobutane and reactions based on it. Chem Heterocycl Compd 33, 805–810 (1997). https://doi.org/10.1007/BF02253030
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DOI: https://doi.org/10.1007/BF02253030