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Synthesis of quinazoline derivatives containing veratrole and benzo-15-crown-5 moieties

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The condensation of (benzo-15-crown-5)-4′-thiocarboxamide with anthranilic acid is studied for the first time. Novel representative of crown ethers incorporating the quinazoline moiety is synthesized. Methylation of (benzo-15-crown-5)-4′-thiocarboxamide proceeds anomalously giving (benzo-15-crown-5)-4′-carbonitrile. (Benzo-15-crown-5)-4′-thiocarboxamide is reacted with thioveratramide in order to compare the reaction paths.

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Additional information

Mirzo Ulugbek Tashkent State University, Tashkent 700095, Republic of Uzbekistan; Institute of Plant Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent 700170. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 937–940, July, 1999.

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Saifullina, N.Z., Ibragimzhanov, K.A., Tashmukhamedova, A.K. et al. Synthesis of quinazoline derivatives containing veratrole and benzo-15-crown-5 moieties. Chem Heterocycl Compd 35, 821–824 (1999). https://doi.org/10.1007/BF02252108

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  • DOI: https://doi.org/10.1007/BF02252108

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