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Synthesis of N-(2-chloroethyl)isatins and their β-ethyleneacetals and β-thiosemicarbazones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The nitrogen atoms of isatin, its 5-bromoderivative, and their β-ethyleneacetals are alkylated by 1,2-dichloroethane in K2CO3−DMF and LiH(NaH)-DMF.

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Institute of Biological Protection of Plants and Institute of Chemistry of the Moldovan Academy of Sciences, Kishinev 2058. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 907–909, July, 1999.

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Rekhter, M.A., Radul, O.M. & Bukhanyuk, S.M. Synthesis of N-(2-chloroethyl)isatins and their β-ethyleneacetals and β-thiosemicarbazones. Chem Heterocycl Compd 35, 792–794 (1999). https://doi.org/10.1007/BF02252101

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  • DOI: https://doi.org/10.1007/BF02252101

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