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7-Dialkylaminomethyl-2,4,5-trimetyl-and 2,4,5-trimethyl-7-phenylminomethyl-1,2,3,4-tetrahydropyrrolo[1,2-c]pyrimidines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The Mannich aminoalkylation of 2,4,5-trimethyl-1,2,3,4-tetrahydropyrrolo[1,2-c]pyrimidine and condensation of its 7-formyl derivative with aniline have been studied. 7-Morpholinomethyl- and 7-(N-methylpiperazinylmethyl)-substituted derivatives have been isolated. 7-Dimenthylaminomethyl- and 7-phenyliminomethyl-substituted derivatives of tetrahydropyrrolo[1,2-c]pyrimidines are easiliy cleaved in the process of chromatographic isolation.

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Russian Peoples' Friendship University, Moscow 117198

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1659–1663, December, 1999.

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Varlamov, A.V., Borisova, T.N., Sorokina, E.A. et al. 7-Dialkylaminomethyl-2,4,5-trimetyl-and 2,4,5-trimethyl-7-phenylminomethyl-1,2,3,4-tetrahydropyrrolo[1,2-c]pyrimidines. Chem Heterocycl Compd 35, 1455–1458 (1999). https://doi.org/10.1007/BF02251822

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  • DOI: https://doi.org/10.1007/BF02251822

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