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Synthesis of nitro- and aminoindoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Optimal conditions are proposed for the direct nitration of 2,3-dimethylindoles containing methyl and methoxy groups in the benzene ring. In contrast to 5- and 6-methylindoles and 5- and 6-methoxyindoles, nitration of 7-methyl-and 7-methoxy-2,3-dimethylindoles proceeds differently under the same conditions. A series of previously unreported aminoindoles was obtained by reduction of the nitroindoles.

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Authors
  1. S. A. Yamashkin
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  2. M. A. Yurovskaya
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Additional information

Mordova State Pedagogical Institute, 430007 Saransk, Russia; e-mail:mgpi@si.moris.ru and M. V. Lomonosov State University, 119899 Moscow, Russia, e-mail:yumar@org.chem.msu.su. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1630–1636, December, 1999.

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Yamashkin, S.A., Yurovskaya, M.A. Synthesis of nitro- and aminoindoles. Chem Heterocycl Compd 35, 1426–1432 (1999). https://doi.org/10.1007/BF02251816

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  • DOI: https://doi.org/10.1007/BF02251816

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