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Synthesis of 17a-ethoximino derivatives of 8-aza-d-homogona-12,17a-diones by annelation of 3,4-dihydroisoquinolines with 2-acetyl-3-ethoximino-5,5-dimethylcyclohexanone

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

[2+4] Cyclocondensation of 3,4-dihydroisoquinolines with 2-acetyl-5,5-dimethyl-3-ethoximinocyclo-hexanone has been used to synthesize the previously unavailable 17a-ethoximino derivatives of 8-aza-D-homogona-12,17a-diones.

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Authors
  1. A. L. Mikhalchuk
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  2. O. V. Gulyakevich
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  3. D. B. Rubinov
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  4. I. L. Rubinova
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  5. A. A. Akhrem
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Additional information

Institute of Bioorganic Chemistry, Belorussian Academy of Sciences, Minsk 220141. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 232–235, February, 1999.

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Mikhalchuk, A.L., Gulyakevich, O.V., Rubinov, D.B. et al. Synthesis of 17a-ethoximino derivatives of 8-aza-d-homogona-12,17a-diones by annelation of 3,4-dihydroisoquinolines with 2-acetyl-3-ethoximino-5,5-dimethylcyclohexanone. Chem Heterocycl Compd 35, 208–210 (1999). https://doi.org/10.1007/BF02251712

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  • DOI: https://doi.org/10.1007/BF02251712

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