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Chemistry of Heterocyclic Compounds

, Volume 35, Issue 1, pp 93–96 | Cite as

Synthesis of heterocycles on the basis of anion arylatied products of unsaturated-compounds. Part 4. Cyclocondensation of 3-aryl-2-halo(thiocyanate)propionitriles

  • N. D. Obushak
  • V. S. Matiichuk
  • R. L. Martyak
  • N. I. Ganushchak
Article

Abstract

Products from the anionic arylation of acrylonitrile show ring closure on interaction with S,N-nucleophiles. The reactions of 3-aryl-2-halopropionitriles with thiourea and ammonium N-phenyldithiocarbamate give respectively 2,4-diimino-5-arylmethylthiazolidines and 4-amino-5-arylmethyl-3-phenyl-4-thiazolin-2-thiones. Hydrogen bromide reacts with 3-aryl-2-thiocyanatopropionitriles to give 4-amino-5-arylmethyl-2-bromothiazoles.

Keywords

Hydrogen Ammonium Bromide Organic Chemistry Thiourea 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic/Plenum 1999

Authors and Affiliations

  • N. D. Obushak
  • V. S. Matiichuk
  • R. L. Martyak
  • N. I. Ganushchak

There are no affiliations available

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